A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 - Université de Montpellier
Article Dans Une Revue Allergy Année : 2020

A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2

Carmen Riggioni (1, 2) , Pasquale Comberiati (3, 4) , Mattia Giovannini (5) , Ioana Agache (6) , Mübeccel Akdis (7) , Magna Alves-Correia (8, 9) , Josep Antó (10, 11, 12) , Alessandra Arcolaci (13) , Ahmet Kursat Azkur (14) , Dilek Azkur (14) , Burcin Beken (15) , Cristina Boccabella (16) , Jean Bousquet (17, 18, 19) , Heimo Breiteneder (20) , Daniela Carvalho (21) , Leticia de Las Vecillas (22) , Zuzana Diamant (23, 24, 25) , Ibon Eguiluz-Gracia (26, 27, 28) , Thomas Eiwegger (29, 30) , Stefanie Eyerich (31, 32) , Wytske Fokkens (33) , Ya-Dong Gao (34) , Farah Hannachi (35) , Sebastian Johnston (36) , Marek Jutel (37, 38) , Aspasia Karavelia (39) , Ludger Klimek (40) , Beatriz Moya (41) , Kari Nadeau (42) , Robyn O'Hehir (43, 44) , Liam O'Mahony (45) , Oliver Pfaar (46) , Marek Sanak (47) , Jürgen Schwarze (48) , Milena Sokolowska (49, 50) , María Torres (27, 28) , Willem van de Veen (49, 50) , Menno van Zelm (43, 44) , de Yun Wang (51) , Luo Zhang (52) , Rodrigo Jiménez-Saiz (53, 54, 55) , Cezmi Akdis (49)
1 Hospital Sant Joan de Déu [Barcelona]
2 Institut de Recerca Pediàtrica Hospital Sant Joan de Déu [Barcelona, Spain]
3 University of Pisa - Università di Pisa
4 Sechenov First Moscow State Medical University
5 UniFI - Università degli Studi di Firenze = University of Florence = Université de Florence
6 Transilvania University of Brasov
7 SIAF - Swiss Institute of Allergy and Asthma Research
8 Hospital CUF Descobertas
9 CINTESIS - Center of Research in Health Technologies and Information Systems
10 ISGlobal - Instituto de Salud Global - Institute For Global Health [Barcelona]
11 IMIM-Hospital del Mar
12 UPF - Universitat Pompeu Fabra [Barcelona]
13 UNIVR - Università degli studi di Verona = University of Verona
14 University of Kirikkale
15 Kanuni Sultan Suleyman Research and Training Hospital [Istanbul]
16 Fondazione Policlinico Universitario Agostino Gemelli IRCCS
17 Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
18 BIH - Berlin Institute of Health
19 MACVIA-LR - Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
20 Medizinische Universität Wien = Medical University of Vienna
21 NOVA - Universidade Nova de Lisboa = NOVA University Lisbon
22 Hospital Universitario Marqués de Valdecilla [Santander]
23 Skane University Hospital [Lund]
24 UK - Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
25 UMCG - University Medical Center Groningen [Groningen]
26 IBIMA Plataforma BIONAND - Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina = Biomedical Research Institute of Málaga and Nanomedicine Platform
27 Hospital Regional Universitario de Málaga = Regional University Hospital of Malaga [Spain]
28 National Network ARADyAL - Allergy Unit [Malaga, Spain]
29 SickKids - The Hospital for sick children [Toronto]
30 University of Toronto
31 CK-CARE, ZAUM - Center of Allergy & Environment
32 HMGU - Helmholtz Zentrum München = German Research Center for Environmental Health
33 Amsterdam UMC - Amsterdam University Medical Center
34 Zhongnan Hospital
35 CHL - Centre Hospitalier de Luxembourg [Luxembourg]
36 NHLI - National Heart and Lung Institute [London]
37 UWr - University of Wrocław [Poland]
38 ALL-MED
39 “Agios Georgios” General Hospital of Chania
40 Center for Rhinology and Allergology = Zentrum für Rhinologie und Allergologie
41 Hospital Universitario 12 de Octubre [Madrid]
42 Sean N. Parker Center for Allergy and Asthma Research [Stanford]
43 Monash University [Melbourne]
44 The Alfred Hospital
45 UCC - University College Cork
46 Philipps Universität Marburg = Philipps University of Marburg
47 UJ - Uniwersytet Jagielloński w Krakowie = Jagiellonian University
48 Edin. - University of Edinburgh
49 SIAF - Swiss Institute of Allergy and Asthma Research
50 CK-CARE - Christine Kühne – Centre for Allergy Research and Education
51 Yong Loo Lin School of Medicine [Singapore]
52 Beijing Tongren Hospital
53 CNB-CSIC - Centro Nacional de Biotecnología [Madrid]
54 McMaster Immunology Research Centre [Ontario, Canada]
55 UFV - Université Francisco de Vitoria = Universidad Francisco de Vitoria
Carmen Riggioni
Hospital Sant Joan de Déu [Barcelona]
Institut de Recerca Pediàtrica Hospital Sant Joan de Déu [Barcelona, Spain]
Pasquale Comberiati
University of Pisa - Università di Pisa
Sechenov First Moscow State Medical University
Mattia Giovannini
Università degli Studi di Firenze = University of Florence = Université de Florence
Ioana Agache
Transilvania University of Brasov
Mübeccel Akdis
Swiss Institute of Allergy and Asthma Research
Magna Alves-Correia
  • Fonction : Auteur
Hospital CUF Descobertas
Center of Research in Health Technologies and Information Systems
Josep Antó
Instituto de Salud Global - Institute For Global Health [Barcelona]
IMIM-Hospital del Mar
Universitat Pompeu Fabra [Barcelona]
Alessandra Arcolaci
  • Fonction : Auteur
Università degli studi di Verona = University of Verona
Ahmet Kursat Azkur
University of Kirikkale
Dilek Azkur
University of Kirikkale
Burcin Beken
Kanuni Sultan Suleyman Research and Training Hospital [Istanbul]
Cristina Boccabella
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Jean Bousquet
Charité - UniversitätsMedizin = Charité - University Hospital [Berlin]
Berlin Institute of Health
Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
Heimo Breiteneder
Medizinische Universität Wien = Medical University of Vienna
Daniela Carvalho
Universidade Nova de Lisboa = NOVA University Lisbon
Leticia de Las Vecillas
Hospital Universitario Marqués de Valdecilla [Santander]
Zuzana Diamant
Skane University Hospital [Lund]
Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
University Medical Center Groningen [Groningen]
Ibon Eguiluz-Gracia
  • Fonction : Auteur
Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina = Biomedical Research Institute of Málaga and Nanomedicine Platform
Hospital Regional Universitario de Málaga = Regional University Hospital of Malaga [Spain]
Allergy Unit [Malaga, Spain]
Thomas Eiwegger
The Hospital for sick children [Toronto]
University of Toronto
Stefanie Eyerich
  • Fonction : Auteur
Center of Allergy & Environment
Helmholtz Zentrum München = German Research Center for Environmental Health
Wytske Fokkens
Amsterdam UMC - Amsterdam University Medical Center
Ya-Dong Gao
  • Fonction : Auteur
Zhongnan Hospital
Farah Hannachi
  • Fonction : Auteur
Centre Hospitalier de Luxembourg [Luxembourg]
Sebastian Johnston
  • Fonction : Auteur
National Heart and Lung Institute [London]
Marek Jutel
University of Wrocław [Poland]
ALL-MED
Aspasia Karavelia
  • Fonction : Auteur
“Agios Georgios” General Hospital of Chania
Ludger Klimek
Center for Rhinology and Allergology = Zentrum für Rhinologie und Allergologie
Beatriz Moya
  • Fonction : Auteur
Hospital Universitario 12 de Octubre [Madrid]
Kari Nadeau
Sean N. Parker Center for Allergy and Asthma Research [Stanford]
Robyn O'Hehir
  • Fonction : Auteur
Monash University [Melbourne]
The Alfred Hospital
Liam O'Mahony
University College Cork
Oliver Pfaar
Philipps Universität Marburg = Philipps University of Marburg
Marek Sanak
Uniwersytet Jagielloński w Krakowie = Jagiellonian University
Jürgen Schwarze
University of Edinburgh
Milena Sokolowska
Swiss Institute of Allergy and Asthma Research
Christine Kühne – Centre for Allergy Research and Education
María Torres
Hospital Regional Universitario de Málaga = Regional University Hospital of Malaga [Spain]
Allergy Unit [Malaga, Spain]
Willem van de Veen
  • Fonction : Auteur
Swiss Institute of Allergy and Asthma Research
Christine Kühne – Centre for Allergy Research and Education
Menno van Zelm
  • Fonction : Auteur
Monash University [Melbourne]
The Alfred Hospital
de Yun Wang
Yong Loo Lin School of Medicine [Singapore]
Luo Zhang
Beijing Tongren Hospital
Rodrigo Jiménez-Saiz
  • Fonction : Auteur
Centro Nacional de Biotecnología [Madrid]
McMaster Immunology Research Centre [Ontario, Canada]
Université Francisco de Vitoria = Universidad Francisco de Vitoria
Cezmi Akdis
Swiss Institute of Allergy and Asthma Research

Résumé

In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date, it has resulted in ~9 million confirmed cases and caused almost 500 000 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socioeconomic crisis of our time. In this context, numerous questions have emerged in demand of basic scientific information and evidence-based medical advice on SARS-CoV-2 and COVID-19. Although the majority of the patients show a very mild, self-limiting viral respiratory disease, many clinical manifestations in severe patients are unique to COVID-19, such as severe lymphopenia and eosinopenia, extensive pneumonia, a "cytokine storm" leading to acute respiratory distress syndrome, endothelitis, thromboembolic complications, and multiorgan failure. The epidemiologic features of COVID-19 are distinctive and have changed throughout the pandemic. Vaccine and drug development studies and clinical trials are rapidly growing at an unprecedented speed. However, basic and clinical research on COVID-19-related topics should be based on more coordinated high-quality studies. This paper answers pressing questions, formulated by young clinicians and scientists, on SARS-CoV-2, COVID-19, and allergy, focusing on the following topics: virology, immunology, diagnosis, management of patients with allergic disease and asthma, treatment, clinical trials, drug discovery, vaccine development, and epidemiology. A total of 150 questions were answered by experts in the field providing a comprehensive and practical overview of COVID-19 and allergic disease.

Domaines

Santé publique et épidémiologie Maladies infectieuses Maladies émergentes Allergologie Pneumologie et système respiratoire

Nathalie Salvy-Córdoba  : Connectez-vous pour contacter le contributeur

https://hal.umontpellier.fr/hal-03609089

Soumis le : mardi 15 mars 2022-12:33:45

Dernière modification le : mardi 17 septembre 2024-10:16:17

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Dates et versions

hal-03609089 , version 1 (15-03-2022)

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Citer

Carmen Riggioni, Pasquale Comberiati, Mattia Giovannini, Ioana Agache, Mübeccel Akdis, et al.. A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2. Allergy, 2020, 75 (10), pp.2503-2541. ⟨10.1111/all.14449⟩. ⟨hal-03609089⟩

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