The pipecolic linker—an acid-labile handle for derivatization of secondary amines on a solid-support. Part 3 - Université de Montpellier
Article Dans Une Revue Tetrahedron Letters Année : 2013

The pipecolic linker—an acid-labile handle for derivatization of secondary amines on a solid-support. Part 3

Résumé

Herein, we demonstrate the versatility of the pipecolic linker for the structural diversification of secondary amines with potential CNS activity. The solid-phase methods elaborated involved N1-indole sulfonylation, nitroindole and nitroarene reduction, and microwave-assisted Buchwald–Hartwig N-arylation.

Domaines

Chimie

Dates et versions

hal-03563368 , version 1 (09-02-2022)

Identifiants

Citer

Paweł Zajdel, Nicolas Masurier, Vittorio Canale, Pascal Verdie, Muriel Amblard, et al.. The pipecolic linker—an acid-labile handle for derivatization of secondary amines on a solid-support. Part 3. Tetrahedron Letters, 2013, 54 (8), pp.998-1002. ⟨10.1016/j.tetlet.2012.12.036⟩. ⟨hal-03563368⟩
15 Consultations
0 Téléchargements

Altmetric

Partager

More