Toward personalization of asthma treatment according to trigger factors
Katarzyna Niespodziana
(1)
,
Kristina Borochova
(1)
,
Petra Pazderova
(1)
,
Thomas Schlederer
(1)
,
Natalia Astafyeva
(2)
,
Tatiana Baranovskaya
(3)
,
Mohamed-Ridha Barbouche
(4)
,
Evgeny Beltyukov
(5)
,
Angelika Berger
(1)
,
Elena Borzova
(6, 7, 8)
,
Jean Bousquet
(9, 10, 11, 12)
,
Roxana Bumbacea
(13)
,
Snezhana Bychkovskaya
(14)
,
Luis Caraballo
(15)
,
Kian Fan Chung
(16)
,
Adnan Custovic
(16)
,
Guillermo Docena
(17)
,
Thomas Eiwegger
(18)
,
Irina Evsegneeva
(8)
,
Alexander Emelyanov
(19)
,
Peter Errhalt
(20)
,
Rustem Fassakhov
(21)
,
Rezeda Fayzullina
(22)
,
Elena Fedenko
(23)
,
Daria Fomina
(8)
,
Zhongshan Gao
(24)
,
Pedro Giavina-Bianchi
(25)
,
Maia Gotua
(26)
,
Susanne Greber-Platzer
(1)
,
Gunilla Hedlin
(27, 28)
,
Natalia Ilina
(23)
,
Zhanat Ispayeva
(29)
,
Marco Idzko
(1)
,
Sebastian Johnston
(16)
,
Ömer Kalayci
(30)
,
Alexander Karaulov
(8)
,
Antonina Karsonova
(8)
,
Musa Khaitov
(23)
,
Elena Kovzel
(31)
,
Marek Kowalski
(32)
,
Dmitry Kudlay
(23)
,
Michael Levin
(33)
,
Svetlana Makarova
(34)
,
Paolo Maria Matricardi
(35)
,
Kari Nadeau
(36)
,
Leyla Namazova-Baranova
(37)
,
Olga Naumova
(38)
,
Oleksandr Nazarenko
(39)
,
Paul O'Byrne
(40)
,
Faith Osier
(41)
,
Alexander Pampura
(7)
,
Carmen Panaitescu
(42)
,
Nikolaos Papadopoulos
(43, 44)
,
Hae-Sim Park
(45)
,
Ruby Pawankar
(46)
,
Wolfgang Pohl
(47, 48)
,
Harald Renz
(49, 50)
,
Ksenja Riabova
(8)
,
Vanitha Sampath
(36)
,
Bülent Sekerel
(30)
,
Elopy Sibanda
(51, 52)
,
Valérie Siroux
(53)
,
Ludmila Sizyakina
(54)
,
Jin-Lyu Sun
(55, 56)
,
Zsolt Szepfalusi
(1)
,
Tetiana Umanets
(38)
,
Hugo van Bever
(57)
,
Marianne van Hage
(28)
,
Margarita Vasileva
(58)
,
Erika von Mutius
(59, 60, 61)
,
Jiu-Yao Wang
(62)
,
Gary Wong
(63)
,
Sergii Zaikov
(39)
,
Mihaela Zidarn
(64, 65)
,
Rudolf Valenta
(1, 8, 23, 28, 66)
1
Medizinische Universität Wien = Medical University of Vienna
2 Saratov State Medical University
3 BelMAPGE - Belarusian Medical Academy of Post-Graduate Education [Minsk]
4 Laboratoire d'immunologie clinique [Institut Pasteur de Tunis]
5 South Ural State Medical University
6 Russian Medical Academy for Continuous Medical Education [Moscow]
7 Pirogov Russian National Research Medical University
8 Sechenov First Moscow State Medical University
9 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
10 MACVIA-LR - Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
11 HU Berlin - Humboldt-Universität zu Berlin = Humboldt University of Berlin = Université Humboldt de Berlin
12 BIH - Berlin Institute of Health
13 UMPCD - University of Medicine and Pharmacy “Carol Davila”
14 KrasSMU - Krasnoyarsk State Medical University
15 Universidad de Cartagena [Cartagena de Indias]
16 NHLI - National Heart and Lung Institute [London]
17 UNLP - Universidad Nacional de la Plata [Argentine]
18 SickKids - The Hospital for sick children [Toronto]
19 North-Western State Medical University [St Petersburg, Russia]
20 Krems University Hospital
21 KFU - Kazan Federal University
22 BASHEDU - Bashkir State University
23 NRC Institute of immunology FMBA
24 ZJSU - Zhejiang Gongshang University [Hangzhou]
25 USP - Universidade de São Paulo = University of São Paulo
26 Tbilisi State University
27 Astrid Lindgren Children's Hospital
28 Karolinska Institutet [Stockholm]
29 KazNU - Al-Farabi Kazakh National University [Almaty]
30 Faculty of Medicine [Hacettepe University]
31 Nazarbayev University [Kazakhstan]
32 MUL - Medical University of Łódź
33 University of Cape Town
34 Dmitry Rogachev National Research Center of Pediatric Hematology
35 Charité - UniversitätsMedizin = Berlin University Medicine
36 Sean N. Parker Center for Allergy and Asthma Research [Stanford]
37 Pirogov Russian National Reasearch Medical University Moscow
38 National Academy of Medical Sciences of Ukraine
39 SNMAPE - Shupyk National Medical Academy of Postgraduate Education [Kiev]
40 Michael DeGroote School of Medicine [Hamilton, ON, Canada]
41 KWTRP - KEMRI-Wellcome Trust Research Programme
42 OncoGen - Pius Branzeu Clinical Emergency Hospital
43 University of Manchester [Manchester]
44 NKUA - National and Kapodistrian University of Athens
45 Ajou University
46 Nippon Medical School [Tokyo, Japon]
47 Hietzing Hospital
48 Karl Landsteiner Institute for Dermatological Research
49 UGMLC - University of Giessen and Marburg Lung Center [Gießen, Germany]
50 German Center for Lung Research
51 UZ - University of Zimbawe [Harare]
52 National University of Science and Technology [Bulawayo]
53 IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble)
54 SFEDU - Southern Federal University [Rostov-on-Don]
55 PUMCH - Peking Union Medical College Hospital [Beijing]
56 China Academy of Chinese Medical Sciences
57 NUS - National University of Singapore
58 Center of Allergology and Clinical Immunology
59 Dr von Hauner Children's Hospital [Munich, Germany]
60 Helmholtz Centre Munich
61 German Centre for Lung Research
62 NCKU - National Cheng Kung University
63 CUHK - The Chinese University of Hong Kong [Hong Kong]
64 Respiratory and Allergic Diseases [Golnik, Slovenia]
65 University of Ljubljana
66 Karl Landsteiner University of Health Sciences - Karl Landsteiner Privatuniversität für Gesundheitswissenschaften [Krems an der Donau, Austria]
2 Saratov State Medical University
3 BelMAPGE - Belarusian Medical Academy of Post-Graduate Education [Minsk]
4 Laboratoire d'immunologie clinique [Institut Pasteur de Tunis]
5 South Ural State Medical University
6 Russian Medical Academy for Continuous Medical Education [Moscow]
7 Pirogov Russian National Research Medical University
8 Sechenov First Moscow State Medical University
9 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
10 MACVIA-LR - Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon
11 HU Berlin - Humboldt-Universität zu Berlin = Humboldt University of Berlin = Université Humboldt de Berlin
12 BIH - Berlin Institute of Health
13 UMPCD - University of Medicine and Pharmacy “Carol Davila”
14 KrasSMU - Krasnoyarsk State Medical University
15 Universidad de Cartagena [Cartagena de Indias]
16 NHLI - National Heart and Lung Institute [London]
17 UNLP - Universidad Nacional de la Plata [Argentine]
18 SickKids - The Hospital for sick children [Toronto]
19 North-Western State Medical University [St Petersburg, Russia]
20 Krems University Hospital
21 KFU - Kazan Federal University
22 BASHEDU - Bashkir State University
23 NRC Institute of immunology FMBA
24 ZJSU - Zhejiang Gongshang University [Hangzhou]
25 USP - Universidade de São Paulo = University of São Paulo
26 Tbilisi State University
27 Astrid Lindgren Children's Hospital
28 Karolinska Institutet [Stockholm]
29 KazNU - Al-Farabi Kazakh National University [Almaty]
30 Faculty of Medicine [Hacettepe University]
31 Nazarbayev University [Kazakhstan]
32 MUL - Medical University of Łódź
33 University of Cape Town
34 Dmitry Rogachev National Research Center of Pediatric Hematology
35 Charité - UniversitätsMedizin = Berlin University Medicine
36 Sean N. Parker Center for Allergy and Asthma Research [Stanford]
37 Pirogov Russian National Reasearch Medical University Moscow
38 National Academy of Medical Sciences of Ukraine
39 SNMAPE - Shupyk National Medical Academy of Postgraduate Education [Kiev]
40 Michael DeGroote School of Medicine [Hamilton, ON, Canada]
41 KWTRP - KEMRI-Wellcome Trust Research Programme
42 OncoGen - Pius Branzeu Clinical Emergency Hospital
43 University of Manchester [Manchester]
44 NKUA - National and Kapodistrian University of Athens
45 Ajou University
46 Nippon Medical School [Tokyo, Japon]
47 Hietzing Hospital
48 Karl Landsteiner Institute for Dermatological Research
49 UGMLC - University of Giessen and Marburg Lung Center [Gießen, Germany]
50 German Center for Lung Research
51 UZ - University of Zimbawe [Harare]
52 National University of Science and Technology [Bulawayo]
53 IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble)
54 SFEDU - Southern Federal University [Rostov-on-Don]
55 PUMCH - Peking Union Medical College Hospital [Beijing]
56 China Academy of Chinese Medical Sciences
57 NUS - National University of Singapore
58 Center of Allergology and Clinical Immunology
59 Dr von Hauner Children's Hospital [Munich, Germany]
60 Helmholtz Centre Munich
61 German Centre for Lung Research
62 NCKU - National Cheng Kung University
63 CUHK - The Chinese University of Hong Kong [Hong Kong]
64 Respiratory and Allergic Diseases [Golnik, Slovenia]
65 University of Ljubljana
66 Karl Landsteiner University of Health Sciences - Karl Landsteiner Privatuniversität für Gesundheitswissenschaften [Krems an der Donau, Austria]
Jean Bousquet
- Fonction : Auteur
- PersonId : 757330
- ORCID : 0000-0002-4061-4766
Thomas Eiwegger
- Fonction : Auteur
- PersonId : 802272
- ORCID : 0000-0002-2914-7829
Alexander Karaulov
- Fonction : Auteur
- PersonId : 802362
- ORCID : 0000-0002-1930-5424
Musa Khaitov
- Fonction : Auteur
- PersonId : 774118
- ORCID : 0000-0003-4961-9640
Dmitry Kudlay
- Fonction : Auteur
- PersonId : 810137
- ORCID : 0000-0003-1878-4467
Michael Levin
- Fonction : Auteur
- PersonId : 775886
- ORCID : 0000-0003-2439-7981
Paolo Maria Matricardi
- Fonction : Auteur
- PersonId : 800461
- ORCID : 0000-0001-5485-0324
Kari Nadeau
- Fonction : Auteur
- PersonId : 798887
- ORCID : 0000-0002-2146-2955
Nikolaos Papadopoulos
- Fonction : Auteur
- PersonId : 763391
- ORCID : 0000-0002-4448-3468
Ruby Pawankar
- Fonction : Auteur
- PersonId : 767956
- ORCID : 0000-0002-3091-7237
Jiu-Yao Wang
- Fonction : Auteur
- PersonId : 819756
- ORCID : 0000-0003-4540-9822
Gary Wong
- Fonction : Auteur
- PersonId : 806608
- ORCID : 0000-0001-5939-812X
Mihaela Zidarn
- Fonction : Auteur
- PersonId : 767976
- ORCID : 0000-0003-0515-5207
Rudolf Valenta
- Fonction : Auteur
Résumé
Asthma is a severe and chronic disabling disease affecting more than 300 million people worldwide. Although in the past few drugs for the treatment of asthma were available, new treatment options are currently emerging, which appear to be highly effective in certain subgroups of patients. Accordingly, there is a need for biomarkers that allow selection of patients for refined and personalized treatment strategies. Recently, serological chip tests based on microarrayed allergen molecules and peptides derived from the most common rhinovirus strains have been developed, which may discriminate 2 of the most common forms of asthma, that is, allergen- and virus-triggered asthma. In this perspective, we argue that classification of patients with asthma according to these common trigger factors may open new possibilities for personalized management of asthma.
| Origine | Publication financée par une institution |
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