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Article Dans Une Revue American Journal of Tropical Medicine and Hygiene Année : 2021

Adaptation of WHO Definitions of Clinical Forms of Chikungunya Virus Infection for the Elderly

Lidvine Godaert
  • Fonction : Auteur
Cécilia Cofais
  • Fonction : Auteur
Fanny Hequet
  • Fonction : Auteur
Emeline Proye
  • Fonction : Auteur
Lukshe Kanagaratnam
  • Fonction : Auteur
Moustapha Dramé

Résumé

ABSTRACT The WHO defined three clinical forms for chikungunya virus infection (CHIKV, namely, acute, atypical, and severe cases) and a chronic form. These definitions seemed inappropriate for the elderly. So, we propose an adapted definition for elderly people. A cross-sectional analysis was performed including patients aged ≥ 65 years, who attended the emergency department with a positive biological diagnosis of CHIKV in 2014. A total of 267 elderly patients (80 ± 8 years) were included. When using the 2015 WHO definitions, 114 patients could not be classified (42.7%) in any of the category, of whom 43 (37.7%) reported absence of fever, 85 (74.6%) reported absence of joint pain, and 14 (12.3%) reported absence of both fever and joint pain. After adaptation of the WHO definitions, the 114 unclassifiable patients were reclassified as follows: eight as typical cases, 50 as atypical cases, 42 as severe cases, and 14 remained unclassifiable. The atypical clinical form was the most common form. The 2015 WHO definitions of the clinical forms at the acute phase of CHIKV are ill suited to the elderly. The adapted definition we propose here appears to be more appropriate and could help improved management of older patients with CHIKV.

Dates et versions

hal-03342139 , version 1 (13-09-2021)

Identifiants

Citer

Lidvine Godaert, Cécilia Cofais, Fanny Hequet, Emeline Proye, Lukshe Kanagaratnam, et al.. Adaptation of WHO Definitions of Clinical Forms of Chikungunya Virus Infection for the Elderly. American Journal of Tropical Medicine and Hygiene, 2021, 104 (1), pp.106-109. ⟨10.4269/ajtmh.20-0761⟩. ⟨hal-03342139⟩
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