Black pigmentation of both forearm bones after chronic minocycline antibiotic therapy for septic nonunion. A case report and literature review - Université de Montpellier Accéder directement au contenu
Article Dans Une Revue Hand Surgery and Rehabilitation Année : 2019

Black pigmentation of both forearm bones after chronic minocycline antibiotic therapy for septic nonunion. A case report and literature review

Pigmentation noire des deux os de l’avant-bras après traitement par minocycline pour pseudarthroseseptique. A propos d’un cas et revue de la littérature

Résumé

We report the case of a 28-year-old man with a septic forearm non-union treated with minocycline for 3 months. At the time of reconstructive surgery, the radius and ulna were entirely black. Surgical debridement until bleeding of both bone extremities resulted in a 5-cm defect that was filled with a cement spacer. Histology confirmed poorly vascularized bone with focal areas of acute inflammatory infiltrate at the non-union sites (highly suggestive of infection) and normal structure of the remaining diaphyseal bones, although black in color. Reconstruction with free vascularized fibula transfer was successful leading to complete bone healing. An incidental finding of minocycline-induced black bone discoloration should not change the surgeon's decision because there is no evidence of adverse effects on bone healing in the literature. Surgery can be performed safely at sites of minocycline-induced black bone pigmentation.
Fichier non déposé

Dates et versions

hal-02565142 , version 1 (06-05-2020)

Identifiants

Citer

A. Toffoli, R. Gamain, C. Lazerges, M. Chammas. Black pigmentation of both forearm bones after chronic minocycline antibiotic therapy for septic nonunion. A case report and literature review. Hand Surgery and Rehabilitation, 2019, 38 (1), pp.71-73. ⟨10.1016/j.hansur.2018.09.008⟩. ⟨hal-02565142⟩
33 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More