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Is combined cataract surgery associated with acute postoperative endophthalmitis? A nationwide study from 2005 to 2014

Abstract : PURPOSE: To assess the incidence of acute postoperative endophthalmitis (POE) after cataract surgery combined with corneal, glaucoma or vitreoretinal surgical procedures from 2005 to 2014 in France. METHODS: In this cohort study, acute POE occurring within 6 weeks after surgery was identified by means of billing codes recorded in a national database in patients operated for cataract extraction with phacoemulsification, or corneal, glaucoma or vitreoretinal surgical procedures, either combined or stand-alone. RESULTS: From January 2005 to December 2014, up to 6 260 477 eyes underwent phacoemulsification cataract surgery as a single procedure and 115 468 eyes underwent phacoemulsification combined with corneal, glaucoma or vitreoretinal surgical procedures. The crude incidence of acute POE after stand-alone or combined cataract surgery was 0.102% and 0.149%, respectively. In multivariate Poisson analysis, combined surgery taken as a whole was at higher risk than cataract stand-alone surgery, with an adjusted incidence rate ratio (IRR) (95% CI) of 1.38 (1.11 to 1.70; p=0.0054). Glaucoma surgeries were associated with a lower acute POE incidence compared with phacoemulsification, conversely to vitreoretinal surgical procedures: IRR 0.63 (0.47 to 0.85; p<0.001) and IRR 1.78 (1.58 to 2.01; p<0.001), respectively. CONCLUSION: A higher incidence of acute POE after combined cataract surgery than after cataract surgery done as a stand-alone procedure was observed based on the French nationwide medical-administrative database. The incidence of acute POE after combined surgery was related to the type of surgery performed simultaneously with cataract extraction.
Keywords : Infection Epidemiology
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https://hal.umontpellier.fr/hal-02550651
Contributeur : Amandine Michel-Avella <>
Soumis le : mercredi 22 avril 2020 - 13:07:09
Dernière modification le : mardi 26 mai 2020 - 16:04:55

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Catherine Creuzot-Garcher, Anne Sophie Mariet, Eric Benzenine, Vincent Daien, Jean-Francois Korobelnik, et al.. Is combined cataract surgery associated with acute postoperative endophthalmitis? A nationwide study from 2005 to 2014. British Journal of Ophthalmology, BMJ Publishing Group, 2019, 103 (4), pp.534-538. ⟨10.1136/bjophthalmol-2018-312171⟩. ⟨hal-02550651⟩

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