Personalizing Breast Cancer Irradiation Using Biology: From Bench to the Accelerator

Abstract : While adjuvant treatments of early breast cancers (BCs) had significantly improved patients' overall survival, some of them will still develop locoregional relapses and/or severe late radio-induced toxicities. Here, we propose to review how to personalize locoregional treatment by identifying patients at high and low risk of locoregional relapse, patients at risk of late radio-induced side effects. We will, therefore, discuss how to enhance BC radiosensitivity. Finally, we will address how personalized radiotherapy could be implemented in prospective clinical trials.
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https://hal.umontpellier.fr/hal-02281437
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Soumis le : lundi 9 septembre 2019 - 11:16:10
Dernière modification le : mardi 10 septembre 2019 - 16:25:15

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David Azria, Muriel Brengues, Sophie Gourgou, Céline Bourgier. Personalizing Breast Cancer Irradiation Using Biology: From Bench to the Accelerator. Frontiers in Oncology, Frontiers, 2018, 8, pp.83. ⟨10.3389/fonc.2018.00083⟩. ⟨hal-02281437⟩

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