From enabling technologies to medicinal mechanochemistry: an eco-friendly access to hydantoin-based active pharmaceutical ingredients
Résumé
The preparation of hydantoin scaffolds using modern non-conventional activation methods is herein described. Special attention is devoted to the preparation of hydantoin-based Active Pharmaceutical Ingredients (APIs) by mechanochemistry, highlighting its advantages compared to classical solution procedures, opening new perspectives in the sustainable preparation of useful scaffolds for the pharmaceutical industry.