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Ganoderma lucidum (Reishi): evidence of efficacy?

Abstract : Rationale: In Asian countries, Ganoderma lucidum is a medicinal mushroom well-known to maintain good health and significantly contribute to longevity [1]. In Traditional Chinese Medicine (TCM), cultivated Reishi is used in numerous forms and pharmaceutical preparations to treat many pathologies and diseases, i.e., asthma, cancers, metabolic syndrome, myopathy… [2]. Method: Different clinical trials and meta-analyses are reported to verify the potential efficacy of this medicinal mushroom. Discussion: The broad spectrum of the biological activities from G. lucidum was investigated based on its chemical composition diversity [1]. Antitumoral activity could be attributed, in vitro, to ganoderic acids with cytotoxic effects on tumoral cell lines. β-D-Glucans are reported for anti-inflammatory and immunomodulatory activities. Recently, evidence of either efficacy or inefficiency of Reishi for the treatment of various pathologies was reported based on clinical trials [3, 4, 5]. Conclusion: Ganoderma lucidum is worldwide marketed as food supplements. The medicinal mushroom focuses on a great deal of hope for the treatment of various pathologies. However, further clinical trials should be essential to demonstrate the real benefit of Reishi on human health.
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Contributeur : Sylvie Rapior <>
Soumis le : mardi 20 août 2019 - 14:07:10
Dernière modification le : mardi 17 mars 2020 - 03:18:29


  • HAL Id : hal-02267069, version 1


Sylvie Morel, Sylvie Rapior, Françoise Fons. Ganoderma lucidum (Reishi): evidence of efficacy?. iCEPS Conference 2019, 7ème edition. Non-pharmacological interventions and preventive, complementary, integrative and personalized medicines, Mar 2019, Montpellier, France. pp.Poster 35, 2019. ⟨hal-02267069⟩



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