Recent progress in research on the pharmacological potential of mushrooms and prospects for their clinical application

Abstract : Fungi are considered one of the most diverse, ecologically significant, and economically important organisms on Earth. The edible and medicinal mushrooms have long been known by humans and were used by ancient civilizations not only as valuable food but also as medicines. Mushrooms are producers of high- and low-molecular-weight bioactive compounds (alkaloids, lectins, lipids, peptidoglycans, phenolics, polyketides, polysaccharides, proteins, polysaccharide-protein/peptides, ribosomal and non-ribosomal peptides, steroids, terpenoids, etc.) possessing more than 130 different therapeutic effects (analgesic, antibacterial, antifungal, anti-inflammatory, antioxidant, antiplatelet, antiviral, cytotoxic, hepatoprotective, hypocholesterolemic, hypoglycemic, hypotensive, immunomodulatory, immunosuppressive, mitogenic/regenerative, etc.). The early record of Materia Medica shows evidence of using mushrooms for treatment of different diseases. Mushrooms were widely used in the traditional medicine of many countries around the world and became great resources for modern clinical and pharmacological research. However, the medicinal and biotechnological potential of mushrooms has not been fully investigated. This review discusses recent advances in research on the pharmacological potential of mushrooms and perspectives for their clinical application.
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Contributeur : Sylvie Rapior <>
Soumis le : vendredi 26 juillet 2019 - 20:29:55
Dernière modification le : mercredi 31 juillet 2019 - 15:46:43

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Susanna M. Badalyan, Anush Barkhudaryan, Sylvie Rapior. Recent progress in research on the pharmacological potential of mushrooms and prospects for their clinical application. Agrawal D. C. (Ed.); Dhansekaran M. (Ed.). Medicinal mushrooms: recent progress in research and development, Springer Nature, pp.1-70, 2019, 978-981-13-6381-8. ⟨10.1007/978-981-13-6382-5_1⟩. ⟨https://link.springer.com/chapter/10.1007%2F978-981-13-6382-5_1⟩. ⟨hal-02196146⟩

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