Late side-effects after curative intent radiotherapy: Identification of hypersensitive patients for personalized strategy

Abstract : Radiation therapy undeniably enhances local control and thus improves overall survival in cancer patients. However, some long-term cancer survivors (less than 10%) develop severe late radio-induced toxicities altering their quality of life. Therefore, there is a need to identify patients who are sensitive to those toxicities and who could benefit from adapted care. In this review, we address all available techniques aiming to detect patients' hyper-radiosensitivity and present the scientific rationales these techniques are based on.
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https://hal.umontpellier.fr/hal-02148578
Contributeur : Cécile Nowak <>
Soumis le : mercredi 5 juin 2019 - 15:54:49
Dernière modification le : vendredi 15 novembre 2019 - 09:49:44

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Céline Bourgier, Jérôme Lacombe, Jérôme Solassol, Alain Mangé, André Pèlegrin, et al.. Late side-effects after curative intent radiotherapy: Identification of hypersensitive patients for personalized strategy. Critical Reviews in Oncology/Hematology, Elsevier, 2015, 93 (3), pp.312-319. ⟨10.1016/j.critrevonc.2014.11.004⟩. ⟨hal-02148578⟩

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