In a workplace, exhaustion/depletion, also known as burnout, may be a source of weakening and wearing of ‘vital’ energy of employees. Beyond the physical and psychological consequences for individuals, a company also suffers the costs of situations of depletion/exhaustion of employees. Drawing on Conservation of Resources theory, we argued that employability is an important personal resource that could help employees in reducing their feelings of being depleted. This study among 209 French employees working in the automotive sector examined the relationship between employability and depletion/exhaustion. Result indicated that two facets of employability (i.e. occupational expertise and balance) were negatively related to exhaustion. These findings suggest that organizations should build family friendly organizational environment, facilitate knowledge sharing, and focus on employees’ personal development to increase the well-being of employees. At the end, theoretical and practical implications are presented.