The efferent projections of the olfactory bulb in Microcebus murinus were identified after transection of the olfactory peduncle and after the revelation of the degenerating fibers by different silver staining methods. Total and partial sections have allowed demonstrating the importance of the two olfactory tracts in the olfactory projection areas. Degenerated fibers and endings were evidence not only in the different telencephalic regions, as classically known, but also in various hypothalamic nuclei (lateral hypothalamus, the suprachiasmatic, posterior supraoptic and mammillary nuclei and in the median eminence) and in several mesencephalic and metencephalic nuclei (ventral tegmental area, interpeduncular and raphe nuclei, and locus coeruleus). In all these structures the degenerate fibers were seen on both sides. The olfactory projections appeared not to be limited to the telencephalic areas. Moreover, the olfactory bulbs seem to be directly connected especially with the vegetative and integrative areas localized in the hypothalamus and the brainstem and particularly with the major aminergic nuclei that play an essential role in the neurovegetative, neuroendocrine and behavioral regulations.