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Article Dans Une Revue Journal of Affective Disorders Année : 2020

Use of a serious game to strengthen medication adherence in euthymic patients with bipolar disorder following a psychoeducational programme: A randomized controlled trial

Résumé

Although psychoeducation programmes are the gold-standard intervention in bipolar disorder (BD), more innovative tools are needed to broaden and consolidate their effects, especially on treatment adherence. Serious games could be an option. Methods: We carried out a two-arm open randomized controlled trial to compare the add-on use of the serious game BIPOLIFE® for one month (n = 20) vs. treatment as usual (TAU; n = 21) following the completion of a psychoeducation programme in euthymic adults with BD. The primary outcome was the percentage of adherent patients (i.e., patients with a Medication Adherence Rating Scale, MARS, total score >7) at 4 months after the end of the psychoeducation programme. We also measured the changes in therapeutic adherence and beliefs on pharmacological treatments (Drug Attitude Inventory, DAI) between study inclusion and the 1-month (end of BIPOLIFE® use) and 4-month visits, healthcare use during the study period, and BIPOLIFE® acceptability.Results: The percentage of adherent patients was lower in the BIPOLIFE® group than in the TAU group at inclusion (p = 0.02). Conversely, the absolute variation of the MARS and DAI scores was higher in the BIPOLIFE® than in the TAU group at the 1-month visit (p = 0.03 and p = 0.002, respectively) but not at the 4-month visit (p = 0.22 and p = 0.07, respectively).Limitations: Small sample size, and low frequency of connexion to BIPOLIFE® declared by the patients.Conclusion: BIPOLIFE® may help patients with BD to increase their confidence in medications, if used regularly.
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hal-03374781 , version 1 (21-07-2022)

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Kathlyne Dupuis Maurin, Chloé Girod, Julia Lou Consolini, Raoul Belzeaux, Bruno Etain, et al.. Use of a serious game to strengthen medication adherence in euthymic patients with bipolar disorder following a psychoeducational programme: A randomized controlled trial. Journal of Affective Disorders, 2020, 262, pp.182-188. ⟨10.1016/j.jad.2019.10.008⟩. ⟨hal-03374781⟩
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