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Article Dans Une Revue Journal of Neurology Année : 2020

Concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia

Résumé

Reversible cerebral vasoconstriction syndrome (RCVS) is a common cause of thunderclap headache (TCH), mainly recurrent, sometimes associated with seizures and/or neurological deficit. Association with amnesia is exceptional. We report a case series of RCVS concomitant with transient global amnesia (TGA) and propose pathophysiologic hypotheses. Methods: We retrospectively reviewed clinical and radiological features of patients diagnosed with confirmed concomitant RCVS and TGA between 2012 and 2018 in two specialized institutions. Results: Two women aged 67 and 53, and a 64-year-old man had a first thunderclap headache triggered by an acute emotional stress, rapidly followed by TGA. Amnesia resolved within a few hours and RCVS was proven for all, with complete resolution of vasospasms within 3 months. All three patients had excellent outcome. Conclusions: RCVS and TGA can occur simultaneously, which suggests common mechanisms such as aberrant responses to physical or emotional stress and cerebral vasoconstriction.
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Dates et versions

hal-03373996 , version 1 (11-10-2021)

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Rosalie Boitet, Nicolas Gaillard, Eddine Bendiab, Lucas Corti, Caroline Roos, et al.. Concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia. Journal of Neurology, 2020, 267 (2), pp.390-394. ⟨10.1007/s00415-019-09594-5⟩. ⟨hal-03373996⟩

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