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Cyclin A2: a genuine cell cycle regulator?

Abstract : Abstract Cyclin A2 belongs to the core cell cycle regulators and participates in the control of both S phase and mitosis. However, several observations suggest that it is also endowed with other functions, and our recent data shed light on its involvement in cytoskeleton dynamic and cell motility. From the transcription of its gene to its posttranslational modifications, cyclin A2 regulation reveals the complexity of the regulatory network shaping cell cycle progression. We summarize our current knowledge on this cell cycle regulator and discuss recent findings raising the possibility that cyclin A2 might play a much broader role in epithelial tissues homeostasis.
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https://hal.umontpellier.fr/hal-03040943
Contributeur : Bénédicte Lemmers Connectez-vous pour contacter le contributeur
Soumis le : vendredi 4 décembre 2020 - 16:16:29
Dernière modification le : mardi 17 mai 2022 - 14:20:03

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Distributed under a Creative Commons Paternité - Pas d'utilisation commerciale - Pas de modification 4.0 International License

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Nawal Bendris, Abdelhalim Loukil, Caroline Cheung, Nikola Arsic, Cosette Rebouissou, et al.. Cyclin A2: a genuine cell cycle regulator?. Biomolecular concepts, De Gruyter, 2012, 3 (6), pp.535-543. ⟨10.1515/bmc-2012-0027⟩. ⟨hal-03040943⟩

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