Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Embryo transfer strategy and therapeutic options in infertile patients with thin endometrium: a systematic review

Abstract : Human endometrium has a key role in implantation process. The measurement of endometrial thickness is the most commonly used in clinical practice. Managing patients with thin endometrium still represents a major challenge for clinicians. The objective of this systematic review was to investigate all available interventions to improve endometrial thickness (EMT) in women with history of thin endometrium undergoing fresh or frozen-thawed embryo transfers (ET). We performed a comprehensive search of relevant studies from January 1978 to February 2018. The different strategies were categorized as hormonal, vascular, and growth factor approaches and specifically analyzed according to the type of ET. Thirty-one studies were included. Overall, quality of the evidence ranged from very low to moderate, with only few randomized controlled trials that support the use of either GnRH analogues in fresh ET or sildenafil in frozen ET for enhancing endometrial growth. Besides, intensified estradiol administration is a common approach that might improve EMT in frozen ET. The present review evidences the paucity of reliable data regarding the efficiency of different interventions aiming at increasing EMT before fresh or frozen-thawed ET. Robust and high-quality randomized controlled trials are still needed before guidelines can be established.
Liste complète des métadonnées

https://hal.umontpellier.fr/hal-02562108
Contributeur : Cécile Nowak <>
Soumis le : lundi 4 mai 2020 - 14:08:48
Dernière modification le : vendredi 15 mai 2020 - 12:22:09

Lien texte intégral

Identifiants

Citation

Noemie Ranisavljevic, Jade Raad, Tal Anahory, Michael Grynberg, Charlotte Sonigo. Embryo transfer strategy and therapeutic options in infertile patients with thin endometrium: a systematic review. Journal of Assisted Reproduction and Genetics, Springer Verlag, 2019, 36 (11), pp.2217-2231. ⟨10.1007/s10815-019-01576-w⟩. ⟨hal-02562108⟩

Partager

Métriques

Consultations de la notice

10