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La toxoplasmose, une complication exceptionnelle mais grave chez le transplanté rénal : à propos de deux observations

Abstract : Toxoplasma infection is uncommon after renal transplantation. As a result, Toxoplasma gondii is often missed from the list of microbial agents which may be responsible of an infectious complication after renal transplantation. However, establishing this diagnosis is very important because toxoplasmosis can be life-threatening in an immunocompromised host, particularly when the diagnosis is too delayed. Here we report two cases of severe toxoplasmosis after renal transplantation. In the first case, primary infection transmitted by a cat developed in a seronegative recipient five years after renal transplantation. In the second case, reactivation of latent infection developed in a seropositive recipient 9 months after transplantation. In both cases, systematic screening for Toxoplasma gondii using polymerase chain reaction (PCR) in biological fluids was essential to suggest the diagnosis. Both recipients rapidly recovered after institution of antiparasitic therapy.
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https://hal.umontpellier.fr/hal-02518585
Contributeur : Nathalie Salvy-Cordoba <>
Soumis le : mercredi 25 mars 2020 - 12:35:38
Dernière modification le : lundi 12 octobre 2020 - 13:58:01

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Sébastien Jugant, Vincent Pernin, Fernando Vetromile, Valerie Garrigue, Sylvie Delmas, et al.. La toxoplasmose, une complication exceptionnelle mais grave chez le transplanté rénal : à propos de deux observations. Néphrologie & Thérapeutique, 2013, 9 (1), pp.32-36. ⟨10.1016/j.nephro.2012.08.004⟩. ⟨hal-02518585⟩

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