Herpes simplex virus type 2 and cancer: A medical geography approach - Université de Montpellier Accéder directement au contenu
Article Dans Une Revue Infection, Genetics and Evolution Année : 2011

Herpes simplex virus type 2 and cancer: A medical geography approach

Résumé

Herpes simplex virus type-2 (HSV-2) has been identified as a possible aetiological agent of cancer in humans, especially prostate cancer, but results remain controversial. Here, we have addressed this question using a medical geography approach based on the national incidence of various cancers and seroprevalence of HSV-2 in 64 countries worldwide. We corrected reports of cancer incidence for national gross domestic product (GDP) because living in a wealthy nation likely increases the probability of having a cancer detected. Data were also corrected for latitude and diet. Our analysis not only confirms that prostate cancer and HSV-2 seroprevalence are positively associated, but it also reveals the existence of a positive relationship between HSV-2 and melanoma incidence in both men and women. These results, though correlational, suggest that HSV-2 should continue to be investigated as a possible oncogenic pathogen of humans.
Fichier principal
Vignette du fichier
Thomas2011.pdf (97.43 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Licence : CC BY - Paternité

Dates et versions

hal-02511283 , version 1 (14-03-2023)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Fréderic Thomas, Eric Elguero, Jacques Brodeur, Jérôme Le Goff, Dorothée Missé. Herpes simplex virus type 2 and cancer: A medical geography approach. Infection, Genetics and Evolution, 2011, 11 (6), pp.1239-1242. ⟨10.1016/j.meegid.2011.04.009⟩. ⟨hal-02511283⟩
55 Consultations
83 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More