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New Insights in Research About Acute Ischemic Myocardial Injury and Inflammation

Abstract : Recognition that inflammation may contribute to the pathogenesis of various cardiac diseases has naturally led to the evaluation of the therapeutic potential of a range of anti-inflammatory approaches. Unfortunately, results in most settings have been disappointing. The majority of novel approaches fail despite promising preclinical data, partly attributable to off-target effects. The purpose of this review, focused on inflammation following acute myocardial ischemia, is to give a brief overview of the new insights regarding research on pro-inflammatory signaling cascades that could be targeted for cardioprotective therapeutic developments.
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https://hal.umontpellier.fr/hal-02506302
Contributeur : Anne Vincent <>
Soumis le : jeudi 12 mars 2020 - 11:35:42
Dernière modification le : vendredi 13 mars 2020 - 01:44:12

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Anne Vincent, Benoit Lattuca, Nolwenn Merlet, Catherine Sportouch-Dukhan, Stéphanie Barrère-Lemaire. New Insights in Research About Acute Ischemic Myocardial Injury and Inflammation. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2013, 12 (1), pp.47-54. ⟨10.2174/1871523011312010007⟩. ⟨hal-02506302⟩

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