Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia - Université de Montpellier Accéder directement au contenu
Article Dans Une Revue Circulation Année : 2012

Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Résumé

Catecholaminergic polymorphic ventricular tachycardia is characterized by stress-triggered syncope and sudden death. Patients with catecholaminergic polymorphic ventricular tachycardia manifest sinoatrial node (SAN) dysfunction, the mechanisms of which remain unexplored.

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Sciences du Vivant [q-bio]

Angelo Torrente  : Connectez-vous pour contacter le contributeur

https://hal.umontpellier.fr/hal-02477214

Soumis le : jeudi 13 février 2020-11:34:15

Dernière modification le : jeudi 29 février 2024-09:14:04

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hal-02477214 , version 1 (13-02-2020)

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Patricia Neco, Angelo Torrente, Pietro Mesirca, Esther Zorio, Nian Liu, et al.. Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT. Circulation, 2012, 126 (4), pp.392-401. ⟨10.1161/CIRCULATIONAHA.111.075382⟩. ⟨hal-02477214⟩

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