Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT

Abstract : Catecholaminergic polymorphic ventricular tachycardia is characterized by stress-triggered syncope and sudden death. Patients with catecholaminergic polymorphic ventricular tachycardia manifest sinoatrial node (SAN) dysfunction, the mechanisms of which remain unexplored.
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https://hal.umontpellier.fr/hal-02477214
Contributeur : Angelo Torrente <>
Soumis le : jeudi 13 février 2020 - 11:34:15
Dernière modification le : vendredi 14 février 2020 - 01:36:51

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Patricia Neco, Angelo Torrente, Pietro Mesirca, Esther Zorio, Nian Liu, et al.. Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT. Circulation, American Heart Association, 2012, 126 (4), pp.392-401. ⟨10.1161/CIRCULATIONAHA.111.075382⟩. ⟨hal-02477214⟩

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