Molecular diagnosis of toxoplasmosis at the onset of symptomatic primary infection: A straightforward alternative to serological examinations - Université de Montpellier Accéder directement au contenu
Article Dans Une Revue International Journal of Infectious Diseases Année : 2019

Molecular diagnosis of toxoplasmosis at the onset of symptomatic primary infection: A straightforward alternative to serological examinations

Résumé

Myopericarditis is a rare but well-documented clinical presentation of primary Toxoplasma gondii infection in immunocompetent patients. Here, early detection of Toxoplasma DNA in the peripheral blood by PCR allowed the diagnosis of acute toxoplasmosis while serological tests were negative. Additional serological evaluations 2 weeks later confirmed the diagnosis and showed that cardiac manifestations occurred before seroconversion. This highlights the importance of a second serological control in the case of a suspected active infection. Overall, we show here that PCR testing for Toxoplasma is a sensitive and straightforward alternative to serological examinations.
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hal-02408741 , version 1 (13-12-2019)

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Paternité - Pas d'utilisation commerciale - Pas de modification

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Maude Lévêque, Delphine Chiffré, Chloé Galtier, Sahar Albaba, Christophe Ravel, et al.. Molecular diagnosis of toxoplasmosis at the onset of symptomatic primary infection: A straightforward alternative to serological examinations. International Journal of Infectious Diseases, 2019, 79, pp.131-133. ⟨10.1016/j.ijid.2018.11.368⟩. ⟨hal-02408741⟩
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