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Article Dans Une Revue American Journal of Tropical Medicine and Hygiene Année : 2018

Serological Evidence of Ebola Virus Infection in Rural Guinea before the 2014 West African Epidemic Outbreak

Résumé

Questions remain as to whether an unnoticed Ebola outbreak occurred in Guinea before the 2014-2016 epidemic. To address this, we used a highly sensitive and specific Luminex-based assay for Ebola virus (EBOV) antibody detection to screen blood samples collected in the framework of the Demographic Health Survey performed in 2012 in Guinea. One sample (GF069) of 1,483 tested was positive at very high immunoglobulin G titer to Zaire EBOV in Guinée Forestière. Thus, at least 2 years before the 2014 EVD outbreak in Guinea, Zaire EBOV was circulating in rural areas of this country.
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Dates et versions

hal-02319899 , version 1 (26-05-2021)

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Alpha Keita, Christelle Butel, Guillaume Thaurignac, Aminata Diallo, Talla Nioke, et al.. Serological Evidence of Ebola Virus Infection in Rural Guinea before the 2014 West African Epidemic Outbreak. American Journal of Tropical Medicine and Hygiene, 2018, 99 (2), pp.425-427. ⟨10.4269/ajtmh.18-0105⟩. ⟨hal-02319899⟩
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