Perception du pronostic des tumeurs mammaires pT1a,b pN0 par la communauté oncologique française : résultats de l’enquête nationale EURISTIC - Université de Montpellier Accéder directement au contenu
Article Dans Une Revue Bulletin du Cancer Année : 2016

[Perception of pT1a,b pN0 breast tumor prognosis by the French oncology community: Results of the EURISTIC national survey].

Perception du pronostic des tumeurs mammaires pT1a,b pN0 par la communauté oncologique française : résultats de l’enquête nationale EURISTIC

Résumé

The prognosis of infracentimetric breast cancers (BC) is heterogeneous. The EURISTIC survey describes how French oncology specialists perceive the prognosis of pT1a,b pN0 BCs. A self-administered questionnaire has been sent to over 2000 French BC specialists. Six hundred and sixty-three physicians responded. Fifty-eight percent do not consider tumor size as a key prognostic criterion. They consider that the cutoff for poor prognosis is 22mm, 10mm and 7mm for hormone receptors (HRs)+, HER2+ and triple-negative (TN) tumors respectively. Eighty-three percent of respondents consider that a HR+ pT1a,b tumor has a good prognosis (21% and 8% for HER2+ and TN respectively). Factors perceived as most detrimental are: HER2 overexpression (29% of respondents); HR- (20%); high grade (20%); TN status (14%); high KI67 (5%); presence of lymphovascular invasion (3%); young age (2%) and high mitotic index (1%). For French specialists, immunohistochemical characteristics, in particular hormone and HER2 status, are strong prognostic factors in BCs below 1cm.

Dates et versions

hal-02299082 , version 1 (27-09-2019)

Identifiants

Citer

Marc Spielmann, Florence Dalenc, Yoann Pointreau, David Azria, Jean-Marc Classe, et al.. Perception du pronostic des tumeurs mammaires pT1a,b pN0 par la communauté oncologique française : résultats de l’enquête nationale EURISTIC. Bulletin du Cancer, 2016, 103 (2), pp.154-163. ⟨10.1016/j.bulcan.2015.10.007⟩. ⟨hal-02299082⟩
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