Groundwater flow systems, into the saturated and unsaturated zones, come from different places depending on the geological, structural and geomorphological configuration of the area. Those which come from places near of recharge zone are known as local flows, and those which come from more distant places from this area are known as intermediate and regional flows. The former have short circulation times from months to years, the latest vary from hundreds to thousands of years. This paper had the aim to identify and to delimit the presence of these groundwater flow systems in the urban hydrogeological system of Aburra Valley –Colombia–, through the analysis of the current hydrogeological model, the variables that characterize groundwater flow systems and hydrochemical information. The results were validated through isotopic analysis. By use of hydrochemical techniques was possible to stablish that the main processes that govern chemical composition of groundwater in the aquifer system are weathering of silicates, dissolution of ferromagnesian minerals, direct ionic exchange, chemical evolution of groundwater and some events of anthropic contamination. By analyzing the variation of chloride and sulphate was found that the main source of these ions is in depth, from intermediate and regional flows. Zones where local, intermediate and regional groundwater flow systems are present were delimitated. Local flows are widely distributed by the study area, are recharged inside the Aburrá river basin, main source of discharge of the area, and are discharged both the slopes and valley. Intermediate and regional flows are recharged outside the Aburrá river basin and discharged exclusively in the valley, near the axis of the river, by vertical upward flows. It was determined that within the aquifer system processes of groundwater mixture from different chemical composition are presented.