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Article Dans Une Revue Muscle & nerve. Supplement. Année : 2015

Orthoptic and video-oculographic analyses in oculopharyngeal muscular dystrophy

Résumé

INTRODUCTION: Mild ophthalmoparesis can be seen in oculopharyngeal muscular dystrophy (OPMD). METHODS: Orthoptic analysis included assessment of phoria/tropia, eye excursion, saccades, pursuit, stereoacuity, and Hess-Lancaster screen test. Video-oculography included fixation, horizontal and vertical saccades, and pursuit. RESULTS: Orthoptic abnormalities were: tropia (4 of 6); abnormal eye excursion (4 of 6, 78% involved lateral or superior rectus muscles); abnormal horizontal or vertical saccades (2 of 6); abnormal pursuit (0 of 6); abnormal stereoacuity (2 of 6); and pathological Hess-Lancaster screen (4 of 6). Video-oculographic abnormalities were present for: fixation (1 of 6); saccade latency (1 of 6); horizontal pursuit (3 of 6); and vertical pursuit (0 of 6). For horizontal saccades, mean velocity, peak velocity, and gain were pathological in 5 of 6, 5 of 6 (61% of pathological mean and peak velocities involved abducting eye movements), and 3 of 6, respectively. For vertical saccades, mean velocity, peak velocity, and gain were pathological in 4 of 6, 4 of 6 (53% involved upward movements), and 3 of 6, respectively. CONCLUSION: The data indicate preferential involvement of lateral and (to a lesser degree) superior rectus muscles in OPMD.

Dates et versions

hal-02122736 , version 1 (07-05-2019)

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Dimitri Renard, Adelaide Ferraro, Marie-Céline Lorenzini, Luc Jeanjean, Marie-Claire Portal, et al.. Orthoptic and video-oculographic analyses in oculopharyngeal muscular dystrophy. Muscle & nerve. Supplement., 2015, 52 (4), pp.554-558. ⟨10.1002/mus.24600⟩. ⟨hal-02122736⟩

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