Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands

Abstract : Glucose-stimulated insulin secretion (GSIS) from pancreatic beta cells is regulated by paracrine factors, the identity and mechanisms of action of which are incompletely understood. Activins are expressed in pancreatic islets and have been implicated in the regulation of GSIS. Activins A and B signal through a common set of intracellular components, but it is unclear whether they display similar or distinct functions in glucose homeostasis.
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https://hal.umontpellier.fr/hal-01904736
Contributeur : Laurianne Adin <>
Soumis le : jeudi 25 octobre 2018 - 11:40:50
Dernière modification le : mardi 28 mai 2019 - 10:38:04

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Haiya Wu, Karima Mezghenna, Patricia Marmol, Tingqing Guo, Annalena Moliner, et al.. Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands. Diabetologia, Springer Verlag, 2014, 57 (1), pp.148 - 156. ⟨10.1007/s00125-013-3079-6⟩. ⟨hal-01904736⟩

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