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Article Dans Une Revue The Journal of Heart and Lung Transplantation Année : 2017

Abnormal pulmonary endothelial cells may underlie the enigmatic pathogenesis of chronic thromboembolic pulmonary hypertension

Résumé

Chronic thromboembolic pulmonary hypertension results from chronic mechanical obstruction of the pulmonary arteries after acute venous thromboembolism. However, the mechanisms that result in the progression from unresolved thrombus to fibrotic vascular remodeling are unknown. We hypothesized that pulmonary artery endothelial cells contribute to this phenomenon via paracrine growth factor and cytokine signaling.
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Dates et versions

hal-01824263 , version 1 (17-12-2019)

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Olaf Mercier, Jennifer Arthur Ataam, Nathaniel Langer, Peter Dorfmüller, Lilia Lamrani, et al.. Abnormal pulmonary endothelial cells may underlie the enigmatic pathogenesis of chronic thromboembolic pulmonary hypertension. The Journal of Heart and Lung Transplantation, 2017, 36 (3), pp.305 - 314. ⟨10.1016/j.healun.2016.08.012⟩. ⟨hal-01824263⟩
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