The paleobiodiversity of the Volutidae (Mollusca: Gastropoda) of the Ranikot Group (Sindh, Pakistan) and particularly ofthe Lakhra Formation (SBZ 5 biozone, Earliest Eocene), is reconsidered on the basis of new material collected during recentfield trips. Ten new species are described (Mitreola brohii sp. nov., Lyrischapa vredenburgi sp. nov., L. brevispirasp. nov., Athleta (Volutopupa) citharopsis sp. nov., A. (Volutocorbis) lasharii sp. nov., Volutilithes welcommei sp. nov.,V. sindhiensis sp. nov., Pseudaulicina coxi sp. nov., Sindhiluta lakhraensis sp. nov. and Pakiluta solangii sp. nov.) andone species is in open nomenclature (Lyria sp.). Three new genera are described: Lyriopsis gen. nov. [Volutinae, ?Lyriini,type species: Lyriopsis cossmanni (Vredenburg, 1923)], Sindhiluta gen. nov. [Volutilithinae, type species: Sindhilutalakhraensis n. sp.] and Pakiluta gen. nov. [?Volutodermatinae, type species: Pakiluta solangii n. sp.]. Two new combinationsare proposed: Lyriopsis cossmanni (Vredenburg, 1923) comb. nov. and Athleta (Volutopupa) intercrenatus (Cossmann& Pissarro, 1909) comb. nov. Lectotypes are designated for Lyria cossmanni Vredenburg, 1923, L. feddeniVredenburg, 1923, Volutospina noetlingi Cossmann & Pissarro, 1909, V. intercrenata Cossmann & Pissarro, 1909 and Athleta(Volutocorbis) victoriae Vredenburg, 1923. With 21 species, this volutid fauna is the most diverse recorded from theTethys Ocean during Earliest Eocene time. The assemblage is characterized by a strong turnover marked by regional speciationand the appearance of many western Tethyan invaders. Although at the species level, the assemblage documents astrong provincialism, at the genus level, the high number of shared genera between Eastern Tethyan and Old WorldTethyan realms begins a phase of long-term homogeneity of volutid assemblages from the Tethyan paleobiogeographicprovince.