Monthly reference change value of cardiac troponin in hemodialysis patients as a useful tool for long-term cardiovascular management

Abstract : Circulating cardiac troponin (cTn) has been identified as a risk factor for cardiovascular and overall mortality in patients undergoing hemodialysis. However, its interpretation remains difficult due to the high prevalence of patients with cTn level beyond the 99th percentile. Determining the cTn reference change value (RCV) may help in assessing a clinically significant change of cTn during regular follow-up of patients. We aimed to determine the long-term RCV of cTn in such patients and to calculate the perdialytic reduction rate of cTn.
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Stéphanie Badiou, A. Boudet, H. Leray-Moragues, A. Rodriguez, Anne-Sophie Bargnoux, et al.. Monthly reference change value of cardiac troponin in hemodialysis patients as a useful tool for long-term cardiovascular management. Clinical Biochemistry, Elsevier, 2016, 49 (15), pp.1195 - 1198. ⟨10.1016/j.clinbiochem.2016.05.015⟩. ⟨hal-01802795⟩

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