Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data

Abstract : Protective mechanical ventilation strategies using low tidal volume or high levels of positive end-expiratory pressure (PEEP) improve outcomes for patients who have had surgery. The role of the driving pressure, which is the difference between the plateau pressure and the level of positive end-expiratory pressure is not known. We investigated the association of tidal volume, the level of PEEP, and driving pressure during intraoperative ventilation with the development of postoperative pulmonary complications.
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Soumis le : samedi 7 décembre 2019 - 10:02:05
Dernière modification le : mardi 10 décembre 2019 - 01:19:39

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Ary Serpa Neto, Sabrine Hemmes, Carmen Barbas, Ana Beiderlinden, Ana Fernandez-Bustamante, et al.. Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respiratory medicine, Elsevier, 2016, 4 (4), pp.272 - 280. ⟨10.1016/S2213-2600(16)00057-6⟩. ⟨hal-01781487⟩

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