Individual hosts and populations frequently harbour multiple parasite species simultaneously. Despite their commonness, the consequences of interspecific interactions among parasites for determining infection outcomes are still poorly understood. We review and propose several expectations for multiple infections involving different species. We highlight that interspecific interactions affect the outcome of competition within hosts and that heterospecific parasites engage in co-transmission, gene exchange and reproductive interference. Studies specifically comparing intra-and interspecific coinfections and knowledge from community ecology may be instrumental to fully understand the consequences of interspecific multiple infections for parasite lifehistory ecology and evolution.