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CT dose optimization for the detection of pulmonary arteriovenous malformation (PAVM): A phantom study

Abstract : To determine the lowest suitable dose level for the detection of pulmonary arteriovenous malformation (PAVM) using a task-based image quality assessment. Material and methods: A phantom was scanned using the standard chest protocol (STD) and 4 other ultra-low dose protocols (ULD) using various kVp. Raw data were reconstructed using level 5 of the hybrid iterative reconstruction algorithm (iDose4) for the STD protocol, and level 6 of iDose4 and levels 1 to 3 of model-based iterative reconstruction (IMR) for the ULD protocols. Both quantitative criteria and qualitative analysis were used to compare protocols. Noise-power-spectrum and Task-based transfer function were computed using imQuest software. The detectability-index (d') was computed for the detection of PAVM. A subjective analysis was performed by 2 chest radiologists to validate the image-quality obtained on the anthropomorphic phantom for all protocols. Results: Similar d' values were found for ULD-140 using iDose4 6 compared to STD protocol. Greater d' values were found for all ULD protocols using IMR compared to STD. Subjective image quality was rated as acceptable to excellent for ULD-140 and ULD-120 for all reconstruction types, for ULD-100 and ULD-80 using IMR2, and for ULD-100 using IMR1. Image smoothing was poor for IMR3 for ULD-100 and ULD-80. Finally, the ULD-80 protocol reconstructed with IMR2 was chosen for the detection of PAVM. With this protocol, the dose (CTDIvol of 0.3mGy) was reduced by 91% compared with the STD protocol. Conclusion: A dose level as low as 0.3mGy reconstructed with IMR2 provides an image quality suitable for the detection of PAVM.
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https://hal.umontpellier.fr/hal-03351399
Contributeur : Nathalie Salvy-Córdoba Connectez-vous pour contacter le contributeur
Soumis le : mercredi 22 septembre 2021 - 12:05:30
Dernière modification le : jeudi 23 septembre 2021 - 10:55:05

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J. Greffier, S. Boccalini, J.P. Beregi, A. Vlassenbroek, A. Vuillod, et al.. CT dose optimization for the detection of pulmonary arteriovenous malformation (PAVM): A phantom study. Diagnostic and Interventional Imaging, Elsevier, 2020, 101 (5), pp.289-297. ⟨10.1016/j.diii.2019.12.009⟩. ⟨hal-03351399⟩

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