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Novel Peptide Marker Corresponding to Salivary Protein gSG6 Potentially Identifies Exposure to Anopheles Bites
Abstract : In order to improve malaria control, and under the aegis of WHO recommendations, many efforts are being devoted to developing new tools for identifying geographic areas with high risk of parasite transmission. Evaluation of the human antibody response to arthropod salivary proteins could be an epidemiological indicator of exposure to vector bites, and therefore to risk of pathogen transmission. In the case of malaria, which is transmitted only by anopheline mosquitoes, maximal specificity could be achieved through identification of immunogenic proteins specific to the Anopheles genus. The objective of the present study was to determine whether the IgG response to the Anopheles gambiae gSG6 protein, from its recombinant form to derived synthetic peptides, could be an immunological marker of exposure specific to Anopheles gambiae bites.
https://hal.umontpellier.fr/hal-02991289
Contributeur : Anne Poinsignon <>
Soumis le : jeudi 5 novembre 2020 - 22:47:38
Dernière modification le : jeudi 3 décembre 2020 - 17:00:02
Contributeur : Anne Poinsignon <>
Soumis le : jeudi 5 novembre 2020 - 22:47:38
Dernière modification le : jeudi 3 décembre 2020 - 17:00:02
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