F. A. Ran, Genome engineering using the CRISPR-Cas9 system, Nat. Protoc, vol.8, pp.2281-2308, 2013.

E. Bushell, Functional profiling of a Plasmodium genome reveals an abundance of essential genes, Cell, vol.170, pp.260-272, 2017.

R. W. Moon, Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes, Proc. Natl. Acad. Sci, vol.110, pp.531-536, 2013.

T. S. Skinner-adams, P. M. Lawrie, P. L. Hawthorne, D. L. Gardiner, and K. R. Trenholme, Comparison of Plasmodium falciparum transfection methods, Malar J, vol.2, pp.1-4, 2003.

F. Caro, M. G. Miller, and J. L. Derisi, Plate-based transfection and culturing technique for genetic manipulation of Plasmodium falciparum, Malar J, vol.11, p.22, 2012.

S. M. Sidik, A Genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes, Cell, vol.166, pp.1423-1435, 2016.

M. J. Gardner, Genome sequence of the human malaria parasite Plasmodium falciparum, Nature, vol.419, pp.498-511, 2002.

M. Ghorbal, Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system, Nat. Biotechnol, vol.32, pp.819-821, 2014.

J. C. Wagner, R. J. Platt, S. J. Goldfless, F. Zhang, and J. C. Niles, Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum, Nat. Methods, vol.11, pp.915-918, 2014.

M. Y. Lim, UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes, Nat. Microbiol, vol.1, p.16166, 2016.

C. L. Ng, CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs, Mol. Microbiol, vol.101, pp.381-393, 2016.

E. Sonoiki, A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue, Nat. Commun, vol.8, p.14574, 2017.

H. Koike-yusa, Y. Li, E. Tan, M. D. Velasco-herrera, and K. Yusa, Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library, Nat. Biotechnol, vol.32, pp.267-273, 2014.

L. A. Gilbert, CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes, Cell, vol.154, pp.442-451, 2013.

M. L. Maeder, CRISPR RNA-guided activation of endogenous human genes, Nat. Methods, vol.10, pp.977-979, 2013.

B. Xiao, Epigenetic editing by CRISPR/dCas9 in Plasmodium falciparum, Proc. Natl. Acad. Sci, vol.116, pp.255-260, 2019.

A. Barcons-simon, C. Cordon-obras, J. Guizetti, J. M. Bryant, and A. Scherf, CRISPR interference of a clonally variant GC-rich noncoding RNA family leads to general repression of var genes in Plasmodium falciparum, MBio, vol.11, issue.1, pp.3054-3119, 2020.
URL : https://hal.archives-ouvertes.fr/hal-02533304

F. Schwach, PlasmoGEM, a database supporting a community resource for large-scale experimental genetics in malaria parasites, Nucleic Acids Res, vol.43, pp.1176-1182, 2015.

A. R. Gomes, A genome-scale vector resource enables high-throughput reverse genetic screening in a malaria parasite, Cell Host Microbe, vol.17, pp.404-413, 2015.

G. G. Van-dooren, Development of the endoplasmic reticulum, mitochondrion and apicoplast during the asexual life cycle of Plasmodium falciparum, Mol. Microbiol, vol.57, pp.405-419, 2005.

M. C. Lee, P. A. Moura, E. A. Miller, and D. A. Fidock, Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif, Mol. Microbiol, vol.68, pp.1535-1546, 2008.

K. Deitsch, C. Driskill, and T. Wellems, Transformation of malaria parasites by the spontaneous uptake and expression of DNA from human erythrocytes, Nucleic Acids Res, vol.29, pp.850-853, 2001.

D. A. Fidock and T. E. Wellems, Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil, Proc. Natl. Acad. Sci. U.S.A, vol.94, pp.10931-10936, 1997.

E. Knuepfer, M. Napiorkowska, C. Van-ooij, and A. A. Holder, Generating conditional gene knockouts in Plasmodium-A toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9, Sci. Rep, vol.7, p.3881, 2017.

N. Regev-rudzki, Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles, Cell, vol.153, pp.1120-1133, 2013.

P. Mantel, Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system, Cell Host Microbe, vol.13, pp.521-534, 2013.

F. Mohring, Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research, Elife, vol.8, p.45829, 2019.

T. F. De-koning-ward, P. R. Gilson, and B. S. Crabb, Advances in molecular genetic systems in malaria, Nat. Rev. Microbiol, vol.13, pp.373-387, 2015.

C. J. Janse, J. Ramesar, and A. P. Waters, High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei, Nat. Protoc, vol.1, pp.346-356, 2006.

S. M. Sidik, C. G. Hackett, F. Tran, N. J. Westwood, and S. Lourido, Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9, PLoS ONE, vol.9, p.100450, 2014.

Y. Wu, L. A. Kirkman, and T. E. Wellems, Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine, Proc. Natl. Acad. Sci, vol.93, pp.1130-1134, 1996.

S. C. Materna and W. Marwan, Estimating the number of plasmids taken up by a eukaryotic cell during transfection and evidence that antisense RNA abolishes gene expression in Physarum polycephalum, FEMS Microbiol. Lett, vol.243, pp.29-35, 2005.

J. Straimer, Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases, Nat. Methods, vol.9, pp.993-998, 2012.

W. Trager and J. B. Jensen, Human malaria parasites in continuous culture, Scientific RepoRtS |, vol.10, pp.673-675, 1976.

A. Radfar, Synchronous culture of Plasmodium falciparum at high parasitemia levels, Nat. Protoc, vol.4, pp.1899-1915, 2009.

C. R. Collins, Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress, PLoS Pathog, vol.9, p.1003344, 2013.

V. Rosario, Cloning of naturally occurring mixed infections of malaria parasites, Science, vol.212, pp.1037-1038, 1981.