Mechanisms linking obesity to insulin resistance and type 2 diabetes, Nature, vol.444, pp.840-846, 2006. ,
Are there still healthy obese patients?, Curr Opin Endocrinol Diabetes Obes, vol.19, pp.341-346, 2012. ,
The metabolically healthy but obese individual presents a favorable inflammation profile, J Clin Endocrinol Metab, vol.90, pp.4145-4150, 2005. ,
Antioxidants and glucose metabolism disorders, Curr Opin Clin Nutr Metab Care, vol.13, pp.439-446, 2010. ,
Inflammatory mechanisms in obesity, Annu Rev Immunol, vol.29, pp.415-445, 2011. ,
Obesity, insulin resistance and free fatty acids, Curr Opin Endocrinol Diabetes Obes, vol.18, pp.139-143, 2011. ,
Inflammation and lipid signaling in the etiology of insulin resistance, Cell Metab, vol.15, pp.635-645, 2012. ,
Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice, Endocrinology, vol.153, pp.5261-5274, 2012. ,
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis, Cell, vol.140, pp.338-348, 2010. ,
PKR-dependent inflammatory signals, Sci Signal, vol.5, p.47, 2010. ,
Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors, Am J Physiol Endocrinol Metab, vol.300, pp.145-154, 2011. ,
Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidasederived superoxide in response to TLR4 activation, Arterioscler Thromb Vasc Biol, vol.29, pp.1370-1375, 2009. ,
Fatty acids modulate Tolllike receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner, J Biol Chem, vol.284, pp.27384-27392, 2009. ,
Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species, Physiol Rev, vol.89, pp.27-71, 2009. ,
Role of insulin-induced reactive oxygen species in the insulin signaling pathway, Antioxid Redox Signal, vol.7, pp.1021-1031, 2005. ,
The peroxide dilemma: opposing and mediating insulin action, Antioxid Redox Signal, vol.15, pp.219-232, 2011. ,
Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress, Diabetologia, vol.49, pp.2463-2473, 2006. ,
Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance, J Endocrinol, vol.197, pp.287-296, 2008. ,
Interferons in autoimmune and inflammatory diseases: regulation and roles, J Interferon Cytokine Res, vol.31, pp.857-865, 2011. ,
Diverse functions of RNase L and implications in pathology, Biochimie, vol.89, pp.789-798, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00167572
Small self-RNA generated by RNase L amplifies antiviral innate immunity, Nature, vol.448, pp.816-819, 2007. ,
An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity, Proc Natl Acad Sci, vol.105, pp.20816-20821, 2008. ,
A newly discovered function for RNase L in regulating translation termination, Nat Struct Mol Biol, vol.12, pp.505-512, 2005. ,
mRNA is an endogenous ligand for Toll-like receptor 3, J Biol Chem, vol.279, pp.12542-12550, 2004. ,
TLR signaling pathways, Semin Immunol, vol.16, pp.3-9, 2004. ,
Toll-like receptors as interferon-regulated genes and their role in disease, J Interferon Cytokine Res, vol.31, pp.13-25, 2011. ,
Cloning and characterization of a RNAse L inhibitor. A new component of the interferon-regulated 2-5A pathway, J Biol Chem, vol.270, pp.13308-13317, 1995. ,
URL : https://hal.archives-ouvertes.fr/hal-01878540
The 2 0 -5 0 oligoadenylate/RNase L/RNase L inhibitor pathway regulates both MyoD mRNA stability and muscle cell differentiation, Mol Cell Biol, vol.20, pp.4959-4969, 2000. ,
RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation, Cell Death Differ, vol.19, pp.1470-1481, 2012. ,
Endoribonuclease L (RNase L) regulates the myogenic and adipogenic potential of myogenic cells, PLoS ONE, vol.4, p.7563, 2009. ,
The metabolic syndrome: role of skeletal muscle metabolism, Ann Med, vol.38, pp.389-402, 2006. ,
Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function, Lipids Health Dis, vol.11, p.30, 2012. ,
Free fatty acidinduced muscle insulin resistance and glucose uptake dysfunction: evidence for PKC activation and oxidative stress-activated signaling pathways, Biochem Biophys Res Commun, vol.389, pp.211-216, 2009. ,
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance, Diabetes, vol.56, pp.1986-1998, 2007. ,
Post-transcriptional regulation of RNase-L expression is mediated by the 3 0 -untranslated region of its mRNA, J Biol Chem, vol.282, pp.7950-7960, 2007. ,
Mapping of the human RNASEL promoter and expression in cancer and normal cells, J Interferon Cytokine Res, vol.25, pp.595-603, 2005. ,
Post-transcriptional gene silencing by siRNAs and miRNAs, Curr Opin Struct Biol, vol.15, pp.331-341, 2005. ,
Decreased insulin responsiveness of glucose uptake in cultured human skeletal muscle cells from insulin-resistant nondiabetic relatives of type 2 diabetic families, Diabetes, vol.49, pp.1169-1177, 2000. ,
Wallberg-Henriksson H. Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects, Diabetes, vol.47, pp.1281-1286, 1998. ,
SOCS-1 and SOCS-3 inhibit IFN-alpha-induced expression of the antiviral proteins 2,5-OAS and MxA, Biochem Biophys Res Commun, vol.320, pp.1007-1014, 2004. ,
Deletion of skeletal muscle SOCS3 prevents insulin resistance in obesity, Diabetes, vol.62, pp.56-64, 2013. ,
Regulation of insulin and leptin signaling by muscle suppressor of cytokine signaling 3 (SOCS3), PLoS ONE, vol.7, p.47493, 2012. ,
RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR, J Biol Chem, vol.278, pp.20124-20132, 2003. ,
TLR3 ligation protects human astrocytes against oxidative stress, J Neuroimmunol, vol.255, pp.54-59, 2013. ,
Proteome analysis of human macrophages reveals the upregulation of manganese-containing superoxide dismutase after toll-like receptor activation, Proteomics, vol.7, pp.378-384, 2007. ,
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation, Cell Metab, vol.12, pp.662-667, 2010. ,
The effect of endurance exercise on both skeletal muscle and systemic oxidative stress in previously sedentary obese men, Nutr Diabetes, vol.3, p.88, 2013. ,
Overexpression of manganese superoxide dismutase ameliorates high-fat diet-induced insulin resistance in rat skeletal muscle, Am J Physiol Endocrinol Metab, vol.303, pp.798-805, 2012. ,
Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase, Proc Natl Acad Sci, vol.101, pp.8852-8857, 2004. ,
Antioxidants prevent health-promoting effects of physical exercise in humans, Proc Natl Acad Sci, vol.106, pp.8665-8670, 2009. ,
Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators, Glia, vol.53, pp.688-695, 2006. ,
Unexpected protective role for Toll-like receptor 3 in the arterial wall, Proc Natl Acad Sci, vol.108, pp.2372-2377, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00609592
Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via Toll-like receptor 3, Inflammation, vol.37, pp.65-70, 2013. ,
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism, Mol Immunol, vol.54, pp.122-131, 2013. ,
Myoblasts from affected and non-affected FSHD muscles exhibit morphological differentiation defects, J Cell Mol Med, vol.14, pp.275-289, 2010. ,
URL : https://hal.archives-ouvertes.fr/inserm-00284424
Increased stability and antiviral activity of 2'-O-phosphoglyceryl derivatives of ,
, Eur J Biochem, vol.142, pp.291-298, 1984.
Caspase-dependent apoptosis by 2',5'-oligoadenylate activation of RNase L is enhanced by IFN-beta, J Interferon Cytokine Res, vol.20, pp.1091-1100, 2000. ,
Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2 0 p)nA) in interferon-treated cells, Nucleic Acids Res, vol.9, pp.1571-1581, 1981. ,
Palmitate induced insulin resistance by PKCtheta-dependent activation of mTOR/S6K pathway in C2C12 myotubes, Exp Clin Endocrinol Diabetes, vol.118, pp.657-661, 2010. ,