DNA replication origin activation in space and time, Nat. Rev. Mol. Cell Biol, vol.16, pp.360-374, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01159618
Replication origins: determinants or consequences of nuclear organization?, Curr. Opin. Genet. Dev, vol.37, pp.67-75, 2016. ,
Eukaryotic chromosome DNA replication: where, when, and how?, Annu. Rev. Biochem, vol.79, pp.89-130, 2010. ,
From structure to mechanism-understanding initiation of DNA replication, Genes Dev, vol.31, pp.1073-1088, 2017. ,
Crystal structure of the eukaryotic origin recognition complex, Nature, vol.519, pp.321-326, 2015. ,
Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases, Cell, vol.146, pp.80-91, 2011. ,
Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins, Mol. Cell, vol.37, pp.247-258, 2010. ,
The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sites, Mol. Cell Biol, vol.15, pp.3023-3031, 1995. ,
Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features ,
URL : https://hal.archives-ouvertes.fr/lirmm-00631491
, Genome Res, vol.21, pp.1438-1449, 2011.
Origins of DNA replication that function in eukaryotic cells, Curr. Opin. Cell Biol, vol.5, pp.434-441, 1993. ,
Eukaryotic DNA replication origins: many choices for appropriate answers, Nat. Rev. Mol. Cell Biol, vol.11, pp.728-738, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00529311
ONCOMINE: a cancer microarray database and integrated data-mining platform, Neoplasia, vol.6, pp.1-6, 2004. ,
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines, J. Cell Biol, vol.17, pp.299-313, 1963. ,
Cyclindependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation, Genes Dev, vol.29, pp.555-566, 2015. ,
MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication, Mol. Biol. Cell, vol.28, pp.2998-3012, 2017. ,
The level of origin firing inversely affects the rate of replication fork progression, J. Cell Biol, vol.201, pp.373-383, 2013. ,
A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity, Nat. Chem. Biol, vol.4, pp.357-365, 2008. ,
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency, J. Clin. Invest, vol.127, 1991. ,
URL : https://hal.archives-ouvertes.fr/hal-01765083
Identification of a heteromeric complex that promotes DNA replication origin firing in human cells, Science, vol.340, pp.981-984, 2013. ,
Mammalian Orc1 protein is selectively released from chromatin and ubiquitinated during the S-to-M transition in the cell division cycle, Mol. Cell Biol, vol.22, pp.105-116, 2002. ,
Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication, Mol. Cell, vol.9, pp.481-491, 2002. ,
A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles, Mol. Cell. Proteom, vol.10, pp.111-013284, 2011. ,
Systematic and quantitative assessment of the ubiquitinmodified proteome, Mol. Cell, vol.44, pp.325-340, 2011. ,
Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes, IUBMB Life, vol.64, pp.136-142, 2012. ,
Defining an embedded code for protein ubiquitination, J. Proteomics Bioinform, vol.2, p.316, 2009. ,
Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest), Nat. Protoc, vol.10, pp.349-361, 2015. ,
The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts, EMBO J, vol.19, pp.5362-5375, 2000. ,
Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity, J. Biol. Chem, vol.288, pp.18939-18946, 2013. ,
an inhibitor of DNA replication, is degraded during mitosis, Cell, vol.93, pp.1043-1053, 1998. ,
Cell cycle-and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1, Genes Dev, vol.14, pp.2330-2343, 2000. ,
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding, J. Biol. Chem, vol.279, pp.19691-19697, 2004. ,
PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication, Nat. Cell Biol, vol.8, pp.84-90, 2006. ,
Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication, Science, vol.346, p.1253596, 2014. ,
Polyubiquitylation drives replisome disassembly at the termination of DNA replication, Science, vol.346, pp.477-481, 2014. ,
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication, Nature, vol.502, pp.249-253, 2013. ,
Orc5 induces large-scale chromatin decondensation in a GCN5-dependent manner, J. Cell Sci, vol.129, pp.417-429, 2016. ,
Immunoaffinity purification of mammalian protein complexes, Methods Enzymol, vol.370, pp.430-444, 2003. ,
A spontaneous Cdt1 mutation in 129 mouse strains reveals a regulatory domain restraining replication licensing, Nat. Commun, vol.4, p.2065, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00852756
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites, Science, vol.316, pp.1198-1202, 2007. ,
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line, Nucleic Acids Res, vol.18, pp.3587-3596, 1990. ,
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei, Nucleic Acids Res, vol.11, pp.1475-1489, 1983. ,
MCM9 is required for mammalian DNA mismatch repair, Mol. Cell, vol.59, pp.831-839, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-02361154
Assembly of the human origin recognition complex occurs through independent nuclear localization of its components, J. Biol. Chem, vol.286, pp.23831-23841, 2011. ,
Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitinproteasome pathway defines a novel paradigm of mitogen-activated protein kinase regulation during cellular differentiation, Mol. Cell Biol, vol.23, pp.4542-4558, 2003. ,
MCM-BP regulates unloading of the MCM2-7 helicase in late S phase, Genes Dev, vol.25, pp.165-175, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00575121
Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase, EMBO J, vol.27, pp.679-691, 2008. ,
Dynamic molecular combing: stretching the whole human genome for high-resolution studies, Science, vol.277, pp.1518-1523, 1997. ,
Monoclonal antibody to 5-bromo-and 5-iododeoxyuridine: a new reagent for detection of DNA replication, Science, vol.218, pp.474-475, 1982. ,
Primary amine oxidase of Escherichia coli Is a metabolic enzyme that can use a human leukocyte molecule as a substrate, PLoS ONE, vol.10, p.142367, 2015. ,
MCM8-and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination, Mol. Cell, vol.47, pp.523-534, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00733290
Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells, J. Cell Biol, vol.140, pp.1285-1295, 1998. ,
SAMHD1 acts at stalled replication forks to prevent interferon induction, Nature, vol.557, pp.57-61, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01791237
Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing, Methods, vol.57, pp.149-157, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00733285