C. R. Anderson, W. G. Downs, G. H. Wattley, N. W. Ahin, and A. A. Reese, Mayaro virus: A new human disease agent. II. Isolation from blood of patients in Trinidad, B.W.I. Am, J. Trop. Med. Hyg, vol.6, pp.1012-1016, 1957.

P. Phillips, D. Lehmann, V. Spooner, J. Barker, S. Tulloch et al., Viruses associated with acute lower respiratory tract infections in children from the eastern highlands of Papua New Guinea (1983-1985), Southeast. Asian J. Trop. Med. Public Health, vol.21, pp.373-382, 1990.

R. B. Tesh, D. M. Watts, K. L. Russell, C. Damodaran, C. Calampa et al., Mayaro virus disease: An emerging mosquito-borne zoonosis in tropical South America, Clin. Infect. Dis, vol.28, pp.67-73, 1999.

M. T. Mota, D. Vedovello, C. Estofolete, C. D. Malossi, J. P. Araujo et al., Complete Genome Sequence of Mayaro Virus Imported from the Amazon Basin to Sao Paulo State, Brazil. Genome Announc, vol.3, 2015.

A. L. Hoch, N. E. Peterson, J. W. Leduc, and F. P. Pinheiro, An outbreak of Mayaro virus disease in Belterra, Brazil. III. Entomological and ecological studies, Am. J. Trop. Med. Hyg, vol.30, pp.689-698, 1981.

F. P. Pinheiro, A. L. Hoch, M. Gomes, and D. R. Roberts, Oropouche virus. IV. Laboratory transmission by Culicoides paraensis, Am. J. Trop. Med. Hyg, vol.30, pp.172-176, 1981.

J. Lednicky, V. M. De-rochars, M. Elbadry, J. Loeb, T. Telisma et al., Virus in Child with Acute Febrile Illness, vol.22, 2000.

R. J. Hassing, I. Leparc-goffart, S. N. Blank, S. Thevarayan, H. Tolou et al., Imported Mayaro virus infection in the Netherlands, J. Infect, vol.61, pp.343-345, 2010.

M. C. Receveur, M. Grandadam, T. Pistone, and D. Malvy, Infection with Mayaro virus in a French traveller returning from the Amazon region, Brazil, Euro Surveill, p.15, 2010.

A. Neumayr, M. Gabriel, J. Fritz, S. Günther, C. Hatz et al., Mayaro virus infection in traveler returning from Amazon Basin, northern Peru, Emerg. Infect. Dis, vol.18, p.695, 2012.

A. M. Powers and . Chikungunya, Clin. Lab. Med, vol.30, pp.209-219, 2010.

A. J. Auguste, J. Liria, N. L. Forrester, D. Giambalvo, M. Moncada et al., Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Emerg. Infect. Dis, vol.21, pp.1742-1750, 2010.

F. W. Santiago, E. S. Halsey, C. Siles, S. Vilcarromero, C. Guevara et al., Long-Term Arthralgia after Mayaro Virus Infection Correlates with Sustained Pro-inflammatory Cytokine Response, PLoS Negl. Trop. Dis, vol.9, 2015.

S. C. Weaver and W. K. Reisen, Present and future arboviral threats, Antivir. Res, vol.85, pp.328-345, 2010.

M. P. Mourao, S. Bastos-mde, R. P. De-figueiredo, J. B. Gimaque, S. Galusso-edos et al., Mayaro fever in the city of Manaus, Brazil, Vector Borne Zoonotic Dis, vol.12, pp.42-46, 2007.

G. C. Smith and D. B. Francy, Laboratory studies of a Brazilian strain of Aedes albopictus as a potential vector of Mayaro and Oropouche viruses, J. Am. Mosq. Control. Assoc, vol.7, pp.89-93, 1991.

K. C. Long, S. A. Ziegler, S. Thangamani, N. L. Hausser, T. J. Kochel et al., Experimental transmission of Mayaro virus by Aedes aegypti, Am. J. Trop. Med. Hyg, vol.85, pp.750-757, 2011.

K. Wiggins, B. Eastmond, and B. W. Alto, Transmission potential of Mayaro virus in Florida Aedes aegypti and Aedes albopictus mosquitoes, Med. Vet. Entomol, vol.32, pp.436-442, 2018.

R. M. Waterhouse, E. V. Kriventseva, S. Meister, Z. Xi, K. S. Alvarez et al., Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes, Science, vol.316, pp.1738-1743, 2007.

Y. Wu, Q. Liu, J. Zhou, W. Xie, C. Chen et al., Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

J. Fros and G. Pijlman, Alphavirus infection: Host cell shut-off and inhibition of antiviral responses, vol.8, p.166, 2016.

F. Aubry, A. Nougairede, L. De-fabritus, G. Querat, E. A. Gould et al., Single-stranded positive-sense RNA viruses generated in days using infectious subgenomic amplicons, J. Gen. Virol, 2014.

T. Atieh, C. Baronti, X. De-lamballerie, and A. Nougairède, Simple reverse genetics systems for Asian and African Zika viruses, Sci. Rep, vol.6, 2016.

P. Surasombatpattana, R. Hamel, S. Patramool, N. Luplertlop, F. Thomas et al., Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses, Infect. Genet. Evol, vol.11, pp.1664-1673, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00623014

G. Manokaran, E. Finol, C. Wang, J. Gunaratne, J. Bahl et al., Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness, Science, vol.350, pp.217-221, 2015.

J. Fox and S. Weisberg, An {R} Companion to Applied Regression, vol.Sage, 2019.

P. M. Russel, B. J. Brewer, S. Klaere, and R. R. Bouckaert, Model selection and parameter inference in phylogenetics using Nested Sampling, Syst. Biol, vol.68, pp.219-233, 2018.

. R-core-team, R: A Language and Environment for Statistical Computing; R Foundation for Statistical Computing, 2018.

W. Tabachnick, G. Wallis, T. H. Aitken, B. Miller, G. Amato et al., Oral infection of Aedes aegypti with yellow fever virus: Geographic variation and genetic considerations, Am. J. Trop. Med. Hyg, vol.34, pp.1219-1224, 1985.

C. F. Bosio, B. J. Beaty, and W. Black, Quantitative genetics of vector competence for dengue-2 virus in Aedes aegypti, Am. J. Trop. Med. Hyg, vol.4, pp.965-970, 1998.

K. Zouache, A. Fontaine, A. Vega-rua, L. Mousson, J. Thiberge et al., Three-way interactions between mosquito population, viral strain and temperature underlying chikungunya virus transmission potential, Proc. R. Soc. B Biol. Sci, vol.281, 2014.
URL : https://hal.archives-ouvertes.fr/pasteur-01680228

T. Chouin-carneiro, A. Vega-rua, M. Vazeille, A. Yebakima, R. Girod et al., Differential susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika virus, PLoS Negl. Trop. Dis, vol.10, 2016.
URL : https://hal.archives-ouvertes.fr/pasteur-01491874

M. R. Kanost and H. Jiang, Clip-domain serine proteases as immune factors in insect hemolymph, Curr. Opin. Insect. Sci, vol.11, pp.47-55, 2015.

Y. Choi, J. F. Fuchs, G. F. Mayhew, E. Y. Helen, and B. M. Christensen, Tissue-enriched expression profiles in Aedes aegypti identify hemocyte-specific transcriptome responses to infection, Insect Biochem. Mol. Biol, vol.42, pp.729-738, 2012.

Z. Xi, J. L. Ramirez, and G. Dimopoulos, The Aedes aegypti toll pathway controls dengue virus infection, PLoS Pathog, 2008.

Z. Zou, J. Souza-neto, Z. Xi, V. Kokoza, S. W. Shin et al., Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity, PLoS Pathog, 2011.

Y. I. Anglero-rodriguez, H. Macleod, S. Kang, J. Carlson, N. Jupatanakul et al., Aedes aegypti Molecular Responses to Zika Virus: Modulation of Infection by the Toll and Jak/Stat Immune Pathways and Virus Host Factors

Y. Dong, R. Aguilar, Z. Xi, E. Warr, E. Mongin et al., Anopheles gambiae immune responses to human and rodent Plasmodium parasite species, PLoS Pathog, 2006.

R. M. Waterhouse, M. Povelones, and G. K. Christophides, Sequence-structure-function relations of the mosquito leucine-rich repeat immune proteins, BMC Genom, vol.11, 2010.

T. M. Colpitts, J. Cox, D. L. Vanlandingham, F. M. Feitosa, G. Cheng et al., Alterations in the Aedes aegypti transcriptome during infection with West Nile, dengue and yellow fever viruses, PLoS Pathog, 2011.

S. K. Behura, C. Gomez-machorro, B. W. Harker, B. Debruyn, D. D. Lovin et al., Global cross-talk of genes of the mosquito Aedes aegypti in response to dengue virus infection, PLoS Negl. Trop. Dis, 1385.

Y. Dong and G. Dimopoulos, Anopheles fibrinogen-related proteins provide expanded pattern recognition capacity against bacteria and malaria parasites, J. Biol. Chem, vol.284, pp.9835-9844, 2009.

E. Rancès, H. Y. Yixin, M. Woolfit, E. A. Mcgraw, and S. L. O'neill, The relative importance of innate immune priming in Wolbachia-mediated dengue interference, PLoS Pathog, vol.8, 2012.

H. Agaisse and N. Perrimon, The roles of JAK/STAT signaling in Drosophila immune responses, Immunol. Rev, vol.198, pp.72-82, 2004.

N. Jupatanakul, S. Sim, and G. Dimopoulos, Aedes aegypti ML and Niemann-Pick type C family members are agonists of dengue virus infection, Dev. Comp. Immunol, vol.43, pp.1-9, 2014.

X. Huang, K. Suyama, J. Buchanan, A. J. Zhu, and M. P. Scott, A Drosophila model of the Niemann-Pick type C lysosome storage disease: Dnpc1a is required for molting and sterol homeostasis, Development, vol.132, pp.5115-5124, 2005.

T. Chang, C. C. Chang, N. Ohgami, and Y. Yamauchi, Cholesterol sensing, trafficking, and esterification, Annu. Rev. Cell Dev. Biol, vol.22, pp.129-157, 2006.

H. Niwa and . Wnt, What's needed to maintain pluripotency? Nat, Cell Biol, vol.13, 1024.

A. Gruber, M. Man?ek, H. Wagner, C. J. Kirschning, and R. Jerala, Structural model of MD-2 and functional role of its basic amino acid clusters involved in cellular lipopolysaccharide recognition, J. Biol. Chem, vol.279, pp.28475-28482, 2004.

E. Starostina, A. Xu, H. Lin, and C. W. Pikielny, A Drosophila protein family implicated in pheromone perception is related to Tay-Sachs GM2-activator protein, J. Biol. Chem, vol.284, pp.585-594, 2009.

J. Horackova, N. Rudenko, M. Golovchenko, and L. Grubhoffer, Der-p2 (Dermatophagoides pteronyssinus) allergen-like protein from the hard tick Ixodes ricinus-a novel member of ML (MD-2-related lipid-recognition) domain protein family, Parasitology, vol.137, pp.1139-1149, 2010.

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