Whole-genome analysis informs breast cancer response to aromatase inhibition, Nature, vol.486, issue.7403, p.3383766, 2012. ,
, Comprehensive molecular portraits of human breast tumours, Nature, vol.490, issue.7418, pp.61-70, 2012.
Deciphering signatures of mutational processes operative in human cancer, PubMed Central PMCID, vol.3, issue.1, p.3588146, 2013. ,
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing, N Engl J Med, vol.366, issue.10, pp.883-92, 2012. ,
Tracking the clonal origin of lethal prostate cancer, J Clin Invest, vol.123, issue.11, 2013. ,
Comparative genomic hybridisation array and DNA sequencing to direct treatment of metastatic breast cancer: a multicentre, prospective trial (SAFIR01/UNICANCER), Lancet Oncol, vol.15, issue.3, p.24508104, 2014. ,
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial, Lancet Oncol, vol.16, issue.13, pp.1324-1358, 2015. ,
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing, Nat Biotechnol, vol.27, issue.2, p.19182786, 2009. ,
Fast and accurate long-read alignment with Burrows-Wheeler transform, Bioinformatics, vol.26, issue.5, p.2828108, 2010. ,
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data, Genome Res, vol.20, issue.9, p.20644199, 2010. ,
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples, Nat Biotechnol, vol.31, issue.3, p.23396013, 2013. ,
Accurate de novo and transmitted indel detection in exome-capture data using microassembly, Nat Methods, vol.11, issue.10, p.25128977, 2014. ,
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3, Fly, vol.6, issue.2, p.3679285, 2012. ,
COSMIC: exploring the world's knowledge of somatic mutations in human cancer, Nucleic Acids Res, vol.43, pp.805-816, 2015. ,
Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data, Ann Oncol, vol.26, issue.1, 2015. ,
Absolute quantification of somatic DNA alterations in human cancer, PubMed Central PMCID, vol.30, issue.5, p.4383288, 2012. ,
Mutational heterogeneity in cancer and the search for new cancer-associated genes, Nature, vol.499, issue.7457, 2013. ,
MuSiC: identifying mutational significance in cancer genomes, Genome Res, vol.22, issue.8, p.22759861, 2012. ,
DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies, PubMed Central PMCID, vol.93, issue.3, p.3769934, 2013. ,
GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers ,
, Genome Biol, vol.12, issue.4, 2011.
deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution, Genome Biol, vol.17, issue.1, p.4762164, 2016. ,
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts, Cell Rep, vol.4, issue.6, p.24055055, 2013. ,
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer, Nat Genet, vol.45, issue.12, 2013. ,
Activating ESR1 mutations in hormoneresistant metastatic breast cancer, Nat Genet, vol.45, issue.12, 2013. ,
Signatures of mutational processes in human cancer, Nature, vol.500, issue.7463, pp.415-436, 2013. ,
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution, Sci Transl Med, vol.7, issue.283, 2015. ,
Impact of chromosomal instability on colorectal cancer progression and outcome, BMC Cancer, vol.14, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-00952435
ESR1 mutations-a mechanism for acquired endocrine resistance in breast cancer, Nat Rev Clin Oncol, vol.12, issue.10, pp.573-83, 2015. ,
Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer, N Engl J Med, vol.373, issue.17, pp.1672-1675, 2015. ,
Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis, Lancet Oncol, vol.16, issue.6, p.25959805, 2015. ,
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer, N Engl J Med, vol.366, issue.6, p.22149876, 2012. ,
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer, N Engl J Med, vol.375, issue.18, pp.1738-1786, 2016. ,
In real life, one-quarter of patients with hormone receptor-positive metastatic breast cancer receive chemotherapy as initial palliative therapy: a study of the Southeast Netherlands Breast Cancer Consortium, Ann Oncol, vol.27, issue.2, pp.256-62, 2016. ,