Cell-cycle dynamics of chromosomal organization at singlecell resolution, Nature, vol.547, pp.61-67, 2017. ,
Regulation of chromatin by histone modifications, Cell Res, vol.21, pp.381-395, 2011. ,
Interpreting the language of histone and DNA modifications, Biochim. Biophys. Acta, vol.1839, pp.627-643, 2014. ,
Chromatin higher-order structure and dynamics, Cold Spring Harb. Perspect. Biol, vol.2, p.596, 2010. ,
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation, Chromosoma, vol.106, pp.348-360, 1997. ,
Chromatin dynamics from S-phase to mitosis: contributions of histone modifications, Cell Tissue Res, vol.356, pp.467-475, 2014. ,
Histone modifications and mitosis: countermarks, landmarks, and bookmarks, Trends Cell Biol, vol.23, pp.175-184, 2013. ,
Mammalian nuclei become licensed for DNA replication during late telophase, J. Cell Sci, vol.115, pp.51-59, 2002. ,
DNA replication origins-where do we begin? Genes Dev, vol.30, pp.1683-1697, 2016. ,
Genetic and epigenetic determinants of DNA replication origins, position and activation, Curr. Opin. Genet. Dev, vol.23, pp.124-131, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-00824364
The histone methyltransferase SET8 is required for S-phase progression, J. Cell Biol, vol.179, pp.1337-1345, 2007. ,
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase, J. Cell Biol, vol.179, pp.1413-1426, 2007. ,
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development, Mol. Cell. Biol, vol.29, pp.2278-2295, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00384522
Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity, Nucleic Acids Res, vol.41, pp.2797-2806, 2013. ,
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position, Nat. Methods, vol.10, pp.1213-1218, 2013. ,
Quantitative analysis of chromatin compaction in living cells using FLIM-FRET, J. Cell Biol, vol.187, pp.481-496, 2009. ,
The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure, Nat. Struct. Mol. Biol, vol.15, pp.1122-1124, 2008. ,
The role of the nucleosome acidic patch in modulating higher order chromatin structure, J. R. Soc. Interface, vol.10, p.20121022, 2013. ,
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability, J. Biol. Chem, vol.283, pp.19478-19488, 2008. ,
Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin, J. Cell Sci, vol.117, pp.4277-4287, 2004. ,
Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo, Cell, vol.160, pp.1145-1158, 2015. ,
Experimental evidence for the influence of molecular crowding on nuclear architecture, J. Cell Sci, vol.120, pp.1673-1680, 2007. ,
Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks, Chromosome Res, vol.14, pp.707-733, 2006. ,
Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination, Mol. Cell, vol.38, pp.452-464, 2010. ,
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins, BMC Biochem, vol.2, p.15, 2001. ,
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing, Cell, vol.139, pp.719-730, 2009. ,
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication, Proc. Natl. Acad. Sci. USA, vol.106, pp.20240-20245, 2009. ,
PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription, Genes Dev, vol.26, pp.325-337, 2012. ,
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells, Nat. Cell Biol, vol.12, pp.1086-1093, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02193626
Cdc7 is an active kinase in human cancer cells undergoing replication stress, J. Biol. Chem, vol.282, pp.208-215, 2007. ,
Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells, Mol. Biol. Cell, vol.17, pp.4459-4472, 2006. ,
Molecular biology: DNA replication reconstructed, Nature, vol.519, pp.418-419, 2015. ,
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks, Cell, vol.141, pp.243-254, 2010. ,
CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation, J. Cell Biol, vol.197, pp.869-876, 2012. ,
Regulating DNA replication in eukarya, Cold Spring Harb. Perspect. Biol, vol.5, p.12930, 2013. ,
Regulated eukaryotic DNA replication origin firing with purified proteins, Nature, vol.519, pp.431-435, 2015. ,
Premature structural changes at replication origins in a yeast minichromosome maintenance (MCM) mutant, J. Biol. Chem, vol.275, pp.18011-18021, 2000. ,
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1, Open Biol, vol.4, p.130138, 2014. ,
Crystal structure of human CDC7 kinase in complex with its activator DBF4, Nat. Struct. Mol. Biol, vol.19, pp.1101-1107, 2012. ,
Reversal of DDKmediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1. Cell Rep, vol.18, pp.2508-2520, 2017. ,
Conformational dynamics of the chromatin fiber in solution: determinants, mechanisms, and functions, Annu. Rev. Biophys. Biomol. Struct, vol.31, pp.361-392, 2002. ,
Chromatin fiber folding: requirement for the histone H4 N-terminal tail, J. Mol. Biol, vol.327, pp.85-96, 2003. ,
Crystal structure of the nucleosome core particle at 2.8 A resolution, Nature, vol.389, pp.251-260, 1997. ,
Nucleosome arrays reveal the two-start organization of the chromatin fiber, Science, vol.306, pp.1571-1573, 2004. ,
The H4 tail domain participates in intra-and internucleosome interactions with protein and DNA during folding and oligomerization of nucleosome arrays, Mol. Cell. Biol, vol.29, pp.538-546, 2009. ,
Nucleosome interactions and stability in an ordered nucleosome array model system, J. Biol. Chem, vol.285, pp.34597-34607, 2010. ,
Chromosome structure dynamics during the cell cycle: a structure to fit every phase, EMBO J, vol.36, pp.2661-2663, 2017. ,
SMC complexes: from DNA to chromosomes, Nat. Rev. Mol. Cell Biol, vol.17, pp.399-412, 2016. ,
SMC complexes differentially compact mitotic chromosomes according to genomic context, Nat. Cell Biol, vol.19, pp.1071-1080, 2017. ,
Condensin-based chromosome organization from bacteria to vertebrates, Cell, vol.164, pp.847-857, 2016. ,
Chromatin controls DNA replication origin selection, lagging-strand synthesis, and replication fork rates, Mol. Cell, vol.65, pp.117-130, 2017. ,
Chromatin constrains the initiation and elongation of DNA replication, Mol. Cell, vol.65, pp.131-141, 2017. ,
Conserved nucleosome positioning defines replication origins, Genes Dev, vol.24, pp.748-753, 2010. ,
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome, Nature, vol.484, pp.115-119, 2012. ,
Chromatin dynamics in genome stability: roles in suppressing endogenous DNA damage and facilitating DNA repair, Int. J. Mol. Sci, vol.18, p.1486, 2017. ,
Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication, EMBO J, vol.36, pp.2726-2741, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02154100
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis, Mol. Cell. Biol, vol.20, pp.8602-8612, 2000. ,
PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest, Genome Res, vol.23, pp.331-340, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02159970
Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex, J. Struct. Biol, vol.140, pp.254-267, 2002. ,
Model-based analysis of ChIP-Seq (MACS) ,
, Genome Biol, vol.9, p.137, 2008.
BEDTools: a flexible suite of utilities for comparing genomic features, Bioinformatics, vol.26, pp.841-842, 2010. ,
An interactive environment for agile analysis and visualization of ChIP-sequencing data, Nat. Struct. Mol. Biol, vol.23, pp.349-357, 2016. ,