Intoxication by Cortinarius orellanus: detection and assay of orellanine in biological fluids and renal biopsies

Abstract : A woman suffering from acute tubulo-interstitial nephritis was admitted to the hospital ten days after deliberate intoxication by ingestion of Cortinarius orellanus. Orellanine, the main toxin responsible for orellanine poisoning, was detected in biological fluids and renal biopsies. It was assayed by direct spectrofluorimetry on two-dimensional thin-layer chromatograms after specific photodecomposition into orelline. The orellanine concentration was 6.12 mg/l in the plasma (10 days after ingestion). Orellanine levels in renal biopsies were 7 micrograms per 25 mm3 of the first biopsy (13 days after ingestion) and 24 micrograms per 8 mm3 of the second biopsy (6 months later).
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal.umontpellier.fr/hal-02196628
Contributeur : Sylvie Rapior <>
Soumis le : lundi 29 juillet 2019 - 10:46:03
Dernière modification le : mercredi 28 août 2019 - 07:32:28

Lien texte intégral

Identifiants

Collections

Citation

Sylvie Rapior, Nadine Delpech, Claude Andary, Gabriel Huchard. Intoxication by Cortinarius orellanus: detection and assay of orellanine in biological fluids and renal biopsies. Mycopathologia, Springer Verlag, 1989, 108 (3), pp.155-161. ⟨10.1007/BF00436220⟩. ⟨hal-02196628⟩

Partager

Métriques

Consultations de la notice

28