E6/E7 mRNA, and p16 INK4a detection in head and neck cancers: a systematic review and meta-analysis, Lancet Oncol, vol.15, pp.1319-1350, 2014. ,
Human papillomavirus and survival of patients with oropharyngeal cancer, N Engl J Med, vol.363, pp.24-35, 2010. ,
Late toxicity after radical treatment for locally advanced head and neck cancer, Oral Oncol, vol.51, pp.795-804, 2015. ,
De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma, Eur J Cancer, vol.50, pp.2636-2684, 2014. ,
Human papillomavirus related oropharyngeal cancer, Ann Oncol, vol.28, pp.2386-98, 2017. ,
Epidermal growth factor receptor biology in head and neck cancer, J Clin Oncol, vol.24, 2006. ,
Oropharyngeal cancers: relationship between epidermal growth factor receptor alterations and human papillomavirus status, Eur J Cancer, vol.50, pp.1100-1111, 2014. ,
Comprehensive genomic characterization of head and neck squamous cell carcinomas, Nature, vol.517, pp.576-82, 2015. ,
PEGFR-Tyr 845 expression as prognostic factors in oral squamous cell carcinoma: a tissue-microarray study with clinic-pathological correlations, Cancer Biol Ther, vol.13, pp.967-77, 2012. ,
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma, Cancer Res, vol.62, pp.7350-7356, 2002. ,
Phosphorylated EGFR at tyrosine 1173 correlates with poor prognosis in oral squamous cell carcinomas, Oral Dis, vol.20, pp.178-85, 2014. ,
Papillomaviruses and cancer: from basic studies to clinical application, Nat Rev Cancer, vol.2, pp.342-50, 2002. ,
Variable expression of the forgotten oncogene E5 in HPV-positive oropharyngeal cancer, J Clin Virol, vol.61, pp.94-100, 2014. ,
The E5 proteins, Virology, vol.445, pp.99-114, 2013. ,
The E5 gene from human papillomavirus type 16 is an oncogene which enhances growth factor-mediated signal transduction to the nucleus, Oncogene, vol.7, pp.19-25, 1992. ,
The E5 oncoprotein of human papillomavirus type 16 inhibits the acidification of endosomes in human keratinocytes, J Virol, vol.69, pp.3185-92, 1995. ,
Double positivity for HPV-DNA/p16 ink4a is the biomarker with strongest diagnostic accuracy and prognostic value for human papillomavirus related oropharyngeal cancer patients, Oral Oncol, vol.78, pp.137-144, 2018. ,
HPV involvement in head and neck cancers: comprehensive assessment of biomarkers in 3680 patients, J Natl Cancer Inst, vol.108, p.403, 2016. ,
Biological evidence for a causal role of HPV16 in a small fraction of laryngeal squamous cell carcinoma, Br J Cancer, vol.109, pp.172-83, 2013. ,
Correlation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review, Br J Cancer, vol.110, pp.1587-94, 2014. ,
Diagnostic accuracy of p16 INK4a immunohistochemistry in oropharyngeal squamous cell carcinomas: a systematic review and meta-analysis, Int J Cancer, vol.140, pp.1186-98, 2017. ,
Human papillomavirus DNA prevalence and type distribution in anal carcinomas worldwide, Int J Cancer, vol.136, pp.98-107, 2015. ,
Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials, Am J Surg Pathol, vol.36, pp.945-54, 2012. ,
Analysis of the integration of human papillomaviruses in head and neck tumours in relation to patients' prognosis, Int J Cancer, vol.138, pp.386-95, 2016. ,
Characterization of HPV and host genome interactions in primary head and neck cancers, Proc Natl Acad Sci, vol.111, pp.15544-15553, 2014. ,
Human viral oncogenesis: a cancer hallmarks analysis, Cell Host Microbe, vol.15, pp.266-82, 2014. ,
EGFR and cancer prognosis, Eur J Cancer, vol.37, pp.9-15, 2001. ,
Genetic landscape of human papillomavirus-associated head and neck cancer and comparison to tobacco-related tumors, J Clin Oncol, vol.33, pp.3227-3261, 2015. ,
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes, Clin Cancer Res, vol.21, pp.870-81, 2015. ,
Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer, J Clin Oncol, vol.26, pp.3128-3165, 2008. ,
EGFR and phosphorylated EGFR in relation to HPV and clinical outcome in tonsillar cancer, Anticancer Res, vol.33, pp.1575-84, 2013. ,
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas, J Clin Oncol, vol.24, pp.4170-4176, 2006. ,
Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma, Cancer Epidemiol Biomarkers Prev, vol.20, pp.1230-1237, 2011. ,
Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma, Oncotarget, vol.7, pp.74362-79, 2016. ,
RTOG Ret 0129/0522 recurrence and HPV status: human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma, J Clin Oncol, vol.32, pp.3365-73, 2014. ,
Panitumumab plus radiotherapy versus chemoradiotherapy in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-2): a randomised, controlled, open-label phase 2 trial, Lancet Oncol, vol.16, pp.221-253, 2015. ,
Concurrent chemoradiotherapy with cisplatin or cetuximab for locally advanced head and neck squamous cell carcinomas: does human papilloma virus play a role?, Oral Oncol, vol.59, pp.50-57, 2016. ,
Radiotherapy plus cisplatin or cetuximab in lowrisk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial, Lancet, 2018. ,
, National Cancer Institute press, 2018.
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial, Lancet, 2018. ,