Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Population structure of a vector of human diseases: Aedes aegypti in its ancestral range, Africa

Abstract : Aedes aegypti, the major vector of dengue, yellow fever, chikungunya, and Zika viruses , remains of great medical and public health concern. There is little doubt that the ancestral home of the species is Africa. This mosquito invaded the New World 400-500 years ago and later, Asia. However, little is known about the genetic structure and history of Ae. aegypti across Africa, as well as the possible origin(s) of the New World invasion. Here, we use ~17,000 genome-wide single nucleotide polymor-phisms (SNPs) to characterize a heretofore undocumented complex picture of this mosquito across its ancestral range in Africa. We find signatures of human-assisted migrations, connectivity across long distances in sylvan populations, and of local ad-mixture between domestic and sylvan populations. Finally, through a phylogenetic analysis combined with the genetic structure analyses, we suggest West Africa and especially Angola as the source of the New World's invasion, a scenario that fits well with the historic record of 16th-century slave trade between Africa and Americas.
Liste complète des métadonnées

Littérature citée [52 références]  Voir  Masquer  Télécharger
Contributeur : Hal Mivegec <>
Soumis le : mercredi 10 octobre 2018 - 16:05:45
Dernière modification le : vendredi 26 février 2021 - 14:00:02
Archivage à long terme le : : vendredi 11 janvier 2019 - 16:44:07


Fichiers éditeurs autorisés sur une archive ouverte




Panayiota Kotsakiozi, Benjamin Evans, Andrea Gloria-Soria, Basile Kamgang, Martin Mayanja, et al.. Population structure of a vector of human diseases: Aedes aegypti in its ancestral range, Africa. Ecology and Evolution, Wiley Open Access, 2018, 8 (16), pp.7835-7848. ⟨10.1002/ece3.4278⟩. ⟨hal-01892439⟩



Consultations de la notice


Téléchargements de fichiers