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Allergen Immunotherapy Outcomes and Unmet Needs Davide Caimmi 947c098f8f48fbbbc267ada2e36ee379 gmail.com davidecaimmi 754264 658887-754264 https://orcid.org/0000-0003-4481-6194 https://www.idref.fr/190361816 Moises A. Calderon 6d59c838e3bc5e70686368ae16c2a55e imperial.ac.uk 933589 983615-933589 Jean Bousquet 757330 178225-757330 https://orcid.org/0000-0002-4061-4766 Pascal Demoly 23f02926435bb7bfb08293ddfbbdc588 inserm.fr pascal-demoly 754222 658889-754222 http://www.researcherid.com/rid/Y-9938-2019 https://www.idref.fr/03442959X https://orcid.org/0000-0001-7827-7964 http://scholar.google.fr/citations?user=So_kniIAAAAJ&hl=fr http://www.researcherid.com/rid/http://www.researcherid.com/rid/Y-9938-2019 Cécile Nowak af8e4130d3a5fb0b188b3bf3b171dc28 inrae.fr 2018-10-03 13:23:01 2025-08-13 03:12:14 2018-10-03 13:23:01 2016-02 contributor Cécile Nowak af8e4130d3a5fb0b188b3bf3b171dc28 inrae.fr CCSD hal-01886919 https://hal.umontpellier.fr/hal-01886919 caimmi:hal-01886919 <i>Immunology and Allergy Clinics of North America</i>, 2016, 36 (1), pp.181 - 189. <a target="_blank" href="https://dx.doi.org/10.1016/j.iac.2015.08.011">⟨10.1016/j.iac.2015.08.011⟩</a> Immunology and Allergy Clinics of North America, 2016, 36 (1), pp.181 - 189. ⟨10.1016/j.iac.2015.08.011⟩ CNRS - Centre national de la recherche scientifique Université Montpellier I Publications du LORIA Université de Montpellier Université de Montpellier (2015-2021) International No Yes Allergen Immunotherapy Outcomes and Unmet Needs Davide Caimmi 947c098f8f48fbbbc267ada2e36ee379 gmail.com davidecaimmi 754264 658887-754264 https://orcid.org/0000-0003-4481-6194 https://www.idref.fr/190361816 Moises A. Calderon 6d59c838e3bc5e70686368ae16c2a55e imperial.ac.uk 933589 983615-933589 Jean Bousquet 757330 178225-757330 https://orcid.org/0000-0002-4061-4766 Pascal Demoly 23f02926435bb7bfb08293ddfbbdc588 inserm.fr pascal-demoly 754222 658889-754222 http://www.researcherid.com/rid/Y-9938-2019 https://www.idref.fr/03442959X https://orcid.org/0000-0001-7827-7964 http://scholar.google.fr/citations?user=So_kniIAAAAJ&hl=fr http://www.researcherid.com/rid/http://www.researcherid.com/rid/Y-9938-2019 14120 0889-8561 Immunology and Allergy Clinics of North America WB Saunders 36 1 181 - 189 2016-02 10.1016/j.iac.2015.08.011 26617234 English Unmet needs Primary end point Clinical outcomes Allergic rhinitis Allergen immunotherapy (AIT) Life Sciences [q-bio]/Immunology/Allergology Life Sciences [q-bio]/Immunology Journal articles Journal articles Journal articles

Allergen immunotherapy (AIT) has been evaluated throughout several studies over the last years. A position paper from the European Academy of Allergy and Clinical Immunology highlighted the total combined symptoms score as the method to record the primary end point in AIT studies for allergic rhinitis, but this score still needs to be formally validated and more work done for other allergic diseases. These aspects still seem to be the main unmet need in the evaluation of AIT clinical outcomes in clinical trials.

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