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            <funder>Les travaux présentés dans cette revue ont été supportés par des fonds européens (Feder), l’aide de la Région Guyane et de la Direction régionale pour la recherche et la technologie dans le cadre des programmes VIRUSES ET RESERVOIRS, un contrat du programme FP7 de la Commission européenne « REGPOT-CT-2011-285837-STRonGer » et un contrat « Investissement d’Avenir » géré par l’Agence nationale de la recherche (CEBA, ref. ANR-10-LABEX-25-01).</funder>
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              <p>Among mammals, rodents play a key role in the emergence of viral diseases. In French Guiana, with 36 rodent species recorded in various ecosystems (pristine forests, savannas, anthropized environments), some natural habitats today encounter anthropogenic perturbations that induce changes in community structure and population dynamics. These modifications are sometimes associated with the circulation and emergence of viral pathogens. For 10 years, investigations on the circulation of two rodent-borne viruses, Hantavirus and Mammarenavirus, are underway in rodent populations as well as in humans for hantavirus. These investigations identified viruses from both genera in their potential reservoirs and allow describing the most favourable habitats for the reservoirs of hantavirus where the risk of viral emergence may be higher. We suggest to investigate how anthropic perturbations in rodent communities can drive the emergence of viruses that are currently confined to a small scale and search for evidence of infection in the human population.</p>
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              <p>Les rongeurs sont décrits comme des réservoirs privilégiés de nom-breuses zoonoses. Du fait de leur forte abondance, de leur dynamique et, pour plusieurs espèces, de leur capacité à coexister avec les populations humaines, les rongeurs jouent un rôle clé dans le maintien et la transmission de pathogènes. En Guyane, 36 espèces de rongeurs ont été recensées et sont présentes aussi bien en forêt primaire et secondaire qu'en savane et en zones urbaines. Certaines populations de rongeurs font face, aujourd'hui, à des perturbations de leurs habitats, du fait des pressions anthropiques. Ces perturbations engendrent des change-ments dans la dynamique des populations et des communautés pouvant avoir un impact sur la circulation et l'émergence des pathogènes. Nous avons récemment identifié des virus appartenant à deux familles virales, Bunyaviridae et Arenavi-dae, dans leurs réservoirs potentiels ainsi que des hantavirus (Bunyaviridae) chez l'homme. De plus, la caractérisation des habitats les plus favorables des espèces réservoirs d'hantavirus a permis de mettre en évidence les zones à plus fort risque d'émergence. Le rôle des communautés de rongeurs doit maintenant être étudié afin de mieux appréhender les mécanismes d'émergence en milieu amazonien.</p>
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          <idno type="program">Laboratoires d'excellence</idno>
          <orgName>CEBA</orgName>
          <desc>CEnter of the study of Biodiversity in Amazonia</desc>
          <date type="start">2010</date>
        </org>
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