, Mol Cell Cardiol, vol.29, pp.1177-1187, 1997.
Role of myosin heavy chain ,
composition in kinetics of force development and Muscle assembly: a titanic achievement? Curr Opin relaxation in rat myocardium, J Physiol, vol.513, pp.18-25, 1998. ,
switching on Ca 2+ activated tension development in 1027-1044. single adult cardiac myocytes, Biophys J, vol.68, 1995. ,
The mechanically 1310-1317. active domain of titin in cardiac muscle, Circ Res, vol.17, pp.856-861 ,
Titins: giant proteins in charge revealed by monoclonal antibodies in imof muscle ultrastructure and elasticity, Science, vol.270, pp.293-296, 1995. ,
, J Cell Biol, vol.106, pp.1563-1572, 1988.
Molecular dissection of N2B cardiac 18, Biophys J, vol.77, pp.3189-3196, 1999. ,
is a three-element molecular spring and is critical 19. MEDUGORAC I. Characterization of intramuscular collagen in the mammalian left ventricle. Basic Res for maintaining thin filament structure, J Cell Biol Cardiol, vol.96, pp.631-644, 1982. ,
,
Series of exon-skipping events in titin's elastic spring 831-837. region as the structural basis for myofibrillar elastic 21, diversity. Circ Res, vol.517, pp.1114-1121, 1999. ,
Folding-unfolding transitions in ,
, Science, vol.276, pp.1112-1116, 1997.
DOUGLAS modulation of cellular stiffness, Differential expression of cardiac titin isoforms and 22, vol.86, 2000. ,
GRANsites in beating canine hearts, Am J Physiol, 1992. ,
Complete unfolding of the titin molecule 136: H293-H306. under external force, Circ Res endogenous sympathetic drive induced by cardiac, vol.122, pp.517-524, 1996. ,
LORENZ ment cytoskeleton-a putative load-bearing struc, Am J Physiol, vol.246, pp.566-572, 1984. ,
Gel electrophoresis of giant modified retinoic acid receptor produces dilated proteins: solubilization and silver-staining of titin cardiomyopathy and congestive heart failure in and nebulin from single muscle fiber segments. transgenic mice, Electrophoresis, vol.100, pp.56-64, 1968. ,
Left ventricular free elasticity of titin in cardiac myocytes: a study using wall and intraventricular pressure-sarcomere length immunoelectron microscopy and cellular mechdistributions, anics. Biophys J, vol.239, pp.430-442, 1980. ,
,
Contributions of collagen matrix to passive left E, SCHAUB MC. Changes in essential myosin light ventricular mechanics in isolated rat hearts, Am J Physiol, vol.266, pp.1007-1018, 1994. ,