B. Chabi, Experimental Gerontology, vol.78, pp.23-31, 2016.

A. C. Mcpherron, A. M. Lee, and S. J. , Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member, Nature, vol.387, pp.83-90, 1977.

C. L. Mendias, K. 1. Bakhurin, J. P. Gumucio, C. S. Davis, and J. A. Faulkner, Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice, Aging Cell, p.24, 2015.

M. R. Morissette, J. C. Stricker, M. A. Rosenberg, C. Buranasombati, E. B. Levitan et al., Effects of myostatin deletion in aging mice, Aging Cell, vol.8, pp.573-583, 2009.

). Mouise, E. Relizani, K. Mille-hamard, L. Denis, R. Hourdé et al., Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle, Am. j. Physiol. Regul. lntegr. Camp. Physiol, vol.307, pp.444-454, 2014.

A. B. Newman, E. M. Simonsick, B. L. Naydeck, and R. M. Boudreau, Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability, JAMA, vol.295, pp.2018-2026, 2006.

M. K. Pagala, K. Ravindran, and T. Namba, Grob D Skeletal muscle fatigue and physical endurance ofyoung and old mice, Muscle Nerve, vol.21, issue.12, pp.1729-1739, 1998.

O. Pansarasa, L. Bertorelli, J. Vecchiet, G. Felzani, and F. Marzatico, Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscle, Free Radie. Bio!. Med, vol.27, pp.617-622, 1999.

M. Pauly, B. Chabi, F. B. Favier, F. Vanterpool, S. Matecki et al., Combined strategies for maintaining skeletal muscle mass and function in aging: myostatin inactivation and AICAR-associated oxidative metabolism induction, J. Gerontol. A Bio!. Sei. Med. Sei, vol.70, pp.1077-1087, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01759577

C. Ploquin, B. Chabi, G. Fouret, B. Vernus, C. Feillet-coudray et al., 2012. 1. ack of myostatin alters intermyofibrillar mitochondria activity, unbalances redox status, and impairs tolerance ta chronic repetitive contractions in muscle, Am. J. Physiol. Endocrinol. Metab, vol.302

S. K. Powers, E. E. Talbert, and P. J. Adhihetty, Reactive oxygen and nitrogen species as intracellular signais in skeletal muscle, j. Physiol, vol.589, pp.2129-2138, 2011.

F. Rahimov, O. D. King, L. C. Warsing, R. E. Powell, C. P. Emerson et al., Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor, Physiol. Genomics, vol.43, issue.8, pp.398-407, 2011.

K. Relizani, ). Mouise, E. Giannesini, B. Hourdé, C. Patel et al., Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy, Mol. Ther, vol.22, p.1423, 2014.

J. Rodriguez, B. Vernus, . Chelh, . Cassar-malek, J. C. Gabillard et al., Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways, Cell. Mol. Life Sei, vol.71, issue.22, pp.4361-4371, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01205103

P. Rustin, D. Chretien, T. Bourgeron, B. Gérard, A. Rôtig et al., Biochemical and molecular investigations in respiratory chain deficiencies. Acta lnt, J. Clin. Chem, vol.228, pp.35-51, 1994.

J. A. Salomon, H. Wang, M. K. Freeman, T. Vos, A. D. Flaxman et al., Healthy life expectancy a systematic analysis for the Global Burden Disease Study, vol.380, pp.2144-2162, 2010.

S. Sriram, S. Subramanian, D. Sathiakumar, M. S. Salerno, C. D. Mcfarlane et al., Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF-KB, Aging Cell, vol.10, pp.931-948, 2011.

D. C. Wharton, A. Tzagoloff, . Ronald, and W. Estabrook, Cytochrome oxidase from beef heart mitochondria, Methods in Enzymology. Academic, pp.245-250, 1967.

T. A. White and N. K. Lebrasseur, Myostatin and sarcopenia: opportunities and challenges-a mini-review, Gerontology, vol.60, issue.4, pp.289-293, 2014.

H. Won, S. Lim, M. Jang, and Y. Kim, Peroxiredoxin-2 upregulated by NF-KB attenuates oxidative stress during the differentiation of muscle-derived C2Cl 2 ce lis, Antioxid. Redox Signal, vol.16, pp.245-261, 2012.

J. Y. Zhou and P. Prognon, Raw material enzymatic activity determination: a specific case for validation and comparison of analytical methods: the example of SOD, J. Pharm. Biomed. Anal, vol.40, pp.1143-1148, 2006.