Genomic imprinting: a mammalian epigenetic discovery model, Annu. Rev. Genet, vol.45, pp.379-403, 2011. ,
Genomic imprinting: the emergence of an epigenetic paradigm, Nat. Rev. Genet, vol.12, pp.565-575, 2011. ,
The role of genomic imprinting in biology and disease: an expanding view, Nat. Rev. Genet, vol.15, pp.517-530, 2014. ,
A systems-level approach to parental genomic imprinting: the Downloaded from, 2015. ,
, 18 10479 imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation, Nucleic Acids Research, vol.45, pp.353-367, 2017.
Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain, EMBO J, vol.16, pp.2814-2825, 1997. ,
Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells, Cancer Res, vol.57, pp.2029-2034, 1997. ,
hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer, Proc. Natl. Acad. Sci. U.S.A, vol.95, pp.8835-8840, 1998. ,
Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors, Oncogene, vol.18, pp.3979-3988, 1999. ,
Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors, Oncogene, vol.14, pp.1973-1979, 1997. ,
Tumor suppressor gene ZAC/PLAGL1: altered expression and loss of the nonimprinted allele in pheochromocytomas, Cancer Genet, vol.204, pp.398-404, 2011. ,
Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck, Head Neck, vol.26, pp.338-344, 2004. ,
The expression of the antiproliferative gene ZAC is lost or highly reduced in nonfunctioning pituitary adenomas, Cancer Res, vol.60, pp.6794-6799, 2000. ,
An imprinted locus associated with transient neonatal diabetes mellitus, Hum. Mol. Genet, vol.9, pp.589-596, 2000. ,
The cell cycle control gene ZAC/PLAGL1 is imprinted-a strong candidate gene for transient neonatal diabetes, Hum. Mol. Genet, vol.9, pp.453-460, 2000. ,
Characterization of the methylation-sensitive promoter of the imprinted ZAC gene supports its role in transient neonatal diabetes mellitus, J. Biol. Chem, vol.276, pp.18653-18656, 2001. ,
Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth, Dev. Cell, vol.11, pp.711-722, 2006. ,
URL : https://hal.archives-ouvertes.fr/inserm-00158399
Preparation, culture, and immortalization of mouse embryonic fibroblasts, Curr. Protoc. Mol. Biol. Ed. Frederick M Ausubel Al, 2005. ,
An intrinsic mechanism of corticogenesis from embryonic stem cells, Nature, vol.455, pp.351-357, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00404043
A scaling normalization method for differential expression analysis of RNA-seq data, Genome Biol, vol.11, p.25, 2010. ,
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data, Bioinforma. Oxf. Engl, vol.26, pp.139-140, 2010. ,
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes, Genome Biol, vol.3, p.34, 2002. ,
An integrated software system for analyzing ChIP-chip and ChIP-seq data, Nat. Biotechnol, vol.26, pp.1293-1300, 2008. ,
Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data, Nucleic Acids Res, vol.38, p.13, 2010. ,
Motif enrichment analysis: a unified framework and an evaluation on ChIP data, BMC Bioinformatics, p.165, 2010. ,
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nat. Protoc, vol.4, pp.44-57, 2009. ,
Sublines of 3T3 cells that accumulate lipids, Cell, vol.1, pp.113-116, 1974. ,
Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines, Mol. Cell. Biol, vol.20, pp.3308-3315, 2000. ,
Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes, Genome Biol, vol.7, p.84, 2006. ,
ChIP-seq and beyond: new and improved methodologies to detect and characterize protein-DNA interactions, Nat. Rev. Genet, vol.13, pp.840-852, 2012. ,
A comparative analysis of genome-wide chromatin immunoprecipitation data for mammalian transcription factors, Nucleic Acids Res, vol.34, p.146, 2006. ,
UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions, Nucleic Acids Res, vol.43, pp.117-122, 2015. ,
An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs, Am. J. Physiol. Regul. Integr. Comp. Physiol, vol.295, pp.189-196, 2008. ,
The candidate tumor suppressor gene ZAC is involved in keratinocyte differentiation and its expression is lost in basal cell carcinomas, Mol. Cancer Res, vol.3, pp.483-492, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00016901
Kip'ing the cell under control, Mol. Cancer Res. MCR, vol.7, pp.1902-1919, 2009. ,
Transcriptional activities of the zinc finger protein Zac are differentially controlled by DNA binding, Mol. Cell. Biol, vol.23, pp.988-1003, 2003. ,
Microarray screening for target genes of the proto-oncogene PLAG1, Oncogene, vol.23, pp.179-191, 2004. ,
The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells, Leukemia, vol.25, pp.655-662, 2011. ,
Peroxisome proliferator-activated receptor gamma is a Zac target gene mediating Zac antiproliferation, Cancer Res, vol.66, pp.11975-11982, 2006. ,
Elevated levels of ZAC1 disrupt neurogenesis and promote rapid in vivo reprogramming, Stem Cell Res, vol.16, pp.1-9, 2016. ,
Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study, Lancet Oncol, vol.10, pp.663-671, 2009. ,
Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta, Hum. Mol. Genet, vol.23, pp.6275-6285, 2014. ,
Genome-wide transcription factor binding: beyond direct target regulation, Trends Genet. TIG, vol.27, pp.141-148, 2011. ,
Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming, Dev. Cell, vol.18, pp.662-674, 2010. ,
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression, Genome Res, vol.19, pp.2172-2184, 2009. ,
Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways, PLoS One, vol.5, p.10870, 2010. ,
Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells, Genome Res, vol.20, pp.1064-1083, 2010. ,
ChIPing the cistrome of PXR in mouse liver, Nucleic Acids Res, vol.38, pp.7943-7963, 2010. ,
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses, Genes Dev, vol.27, pp.1016-1031, 2013. ,
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm, PLoS Biol, vol.6, p.27, 2008. ,
Pioneer transcription factors: establishing competence for gene expression, Genes Dev, vol.25, pp.2227-2241, 2011. ,
Transcription factors: specific DNA binding and specific gene regulation, Trends Genet. TIG, vol.30, pp.211-219, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-00994961