Induction of the neural crest and the opportunities of life on the edge, Dev Biol, vol.275, pp.1-11, 2004. ,
Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem clls, Curr Pharm Biotechnol, vol.12, pp.160-70, 2011. ,
,
Multipotentiality of the neural crest, Curr Opin Genet Dev, vol.13, pp.529-565, 2003. ,
,
Assembling neural crest regulatory circuits into a gene regulatory network, Annu Rev Cell Dev Biol, vol.26, pp.581-603, 2010. ,
Essential role of non-canonical Wnt signalling in neural crest migration, Development, vol.132, pp.2587-97, 2005. ,
,
Epithelial-mesenchymal transitions in development and disease, Cell, vol.139, pp.871-90, 2009. ,
Taking Rho GTPases to the next level: the cellular functions of atypical Rho GTPases, Exp Cell Res, vol.313, pp.3673-3682, 2007. ,
,
Regulation of XSnail2 expression by Rho GTPases, Dev Dyn, vol.236, pp.2555-66, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00284041
A role for rhoB in the delamination of neural crest cells from the dorsal neural tube, Development, vol.125, pp.5055-67, 1998. ,
Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA, Development, vol.135, pp.1771-80, 2008. ,
,
Evolution of the Rho family of ras-like GTPases in eukaryotes, Mol Biol Evol, vol.24, pp.203-219, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-02267395
Activity of the RhoU/ Wrch1 GTPase is critical for cranial neural crest cell migration, Dev Biol, vol.350, pp.451-63, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-02267377
,
The small GTPase RhoV is an essential regulator of neural crest induction in Xenopus, Dev Biol, vol.310, pp.113-141, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-02267391
Wrch1 is a GTPasedeficient Cdc42-like protein with unusual binding characteristics and cellular effects, Exp Cell Res, vol.299, pp.356-69, 2004. ,
Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase, Curr Biol, vol.14, pp.2052-2058, 2004. ,
,
Critical and distinct roles of amino-and carboxyl-terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase, J Biol Chem, vol.280, pp.13784-92, 2005. ,
,
Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp. Biochem J, vol.404, pp.487-97, 2007. ,
,
Signalling to cancer cell invasion through PAK family kinases, Front Biosci Landmark, vol.16, pp.849-64, 2011. ,
,
Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions, Cancer Res, vol.65, pp.3179-84, 2005. ,
Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest, Development, vol.130, pp.483-94, 2003. ,
A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly, PLoS One, vol.5, 2011. ,
Neural tube closure in Xenopus laevis involves medial migration, directed protrusive activity, cell intercalation and convergent extension, Development, vol.126, pp.4547-56, 1999. ,
The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/ STAT3 and Wnt-1 pathways, Biochem J, vol.421, pp.283-92, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00479149
Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1, Genes Dev, vol.15, pp.1796-807, 2001. ,
,
The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration, J Cell Sci, vol.120, pp.1927-1961, 2007. ,
Identification of a bipartite focal adhesion localization signal in RhoU/Wrch-1, a Rho family GTPase that regulates cell adhesion and migration, Biol Cell, vol.99, pp.701-717, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-02323488
,
GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration, Mol Biol Cell, vol.22, pp.2119-2149, 2011. ,
Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis, Current Biology, vol.11, issue.01, pp.198-199, 2001. ,
Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation, Development, vol.135, pp.2603-2617, 2008. ,
Requirement for neuregulin receptor erbB2 in neural and cardiac development, Nature, vol.378, pp.394-402, 1995. ,
,
Regulation of the Rho family small GTPase Wrch-1/ RhoU by C-terminal tyrosine phosphorylation requires Src, Mol Cell Biol, vol.30, pp.4324-4362, 2010. ,
,
A Src-Tks5 Pathway Is Required for Neural Crest Cell Migration during Embryonic Development, PLoS One, vol.6, 2011. ,
,
Rho GTPases have diverse effects on the organization of the actin filament system, Biochem J, vol.377, pp.327-364, 2004. ,
,
The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamics, Mol Cell Biol, vol.28, pp.1802-1816, 2008. ,
,
Pyk2 activation triggers epidermal growth factor receptor signaling and cell motility after wounding sheets of epithelial cells, J Biol Chem, vol.285, pp.13372-13381, 2010. ,
,
The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis, Mol Cell Biol, vol.29, pp.1035-1084, 2009. ,
,
Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity, J Cell Biol, vol.178, pp.355-61, 2007. ,
,
Wnt signaling pathways meet Rho GTPases, Genes Dev, vol.23, pp.265-77, 2009. ,
,
Integrating chemotaxis and contact-inhibition during collective cell migration: Small GTPases at work, Small Gtpases, vol.1, pp.113-120, 2010. ,
,
Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations, Dev Biol, vol.340, pp.613-638, 2011. ,
Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1, Cell Stem Cell, vol.4, pp.236-283, 2009. ,
,
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways, Nat Rev Clin Oncol, vol.8, pp.97-106, 2011. ,
,