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Réparation de l’ADN et longévité : les rongeurs et nous : Chroniques génomiques

Abstract : Large differences in maximum longevity exist between different rodent species. Determination of the spontaneous and mutagen-induced mutation rates in these species by single (somatic) cell sequencing suggests more efficient DNA repair in long-lived species (including humans), but the data is too noisy to prove a strong correlation between longevity and preservation of DNA integrity.
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https://hal.archives-ouvertes.fr/hal-03620427
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Submitted on : Friday, March 25, 2022 - 9:57:40 PM
Last modification on : Tuesday, May 24, 2022 - 10:59:33 AM
Long-term archiving on: : Sunday, June 26, 2022 - 7:14:10 PM

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Bertrand Jordan. Réparation de l’ADN et longévité : les rongeurs et nous : Chroniques génomiques. médecine/sciences, EDP Sciences, 2022, 38 (3), pp.317-319. ⟨10.1051/medsci/2022019⟩. ⟨hal-03620427⟩

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